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Physician Assistant (PANCE) Practice Test 2
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Avg score: 76% • Most missed: “A 46-year-old obese male presents in the emergency room with acute myocardial in…”
The material on the PANCE and PANRE is organized by the NCCPA into two dimensions, as indicated in the content blueprint for the examination. - Organ systems and the diseases, disorders and medical assessments physician assistants encounter within those systems; and - The knowledge and skills physician assistants should exhibit when confronted with those diseases, disorders and assessments. Medical Content Categories % Allocation: Cardiovascular System 13% Dermatologic System 5% Endocrine System 7% Eyes, Ears, Nose, and Throat 7% Gastrointestinal System/Nutrition 9% Genitourinary... Show more
Physician Assistant (PANCE) Practice Test 2
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25 Questions

1. A 28-year-old obese male presents with muscle weakness, headache, backache, acne, and erectile dysfunction. Laboratory results reveal free cortisol in the urine measuring 142 mg/dL and plasma cortisol of 13 mg/dL. CT scan of the abdomen reveals the presence of an adrenocortical tumor. Based on the patient’s presentation, lab results, and diagnostic studies, which of the following is the most accurate diagnosis?
2. A 44-year-old female presents with pain in the inner ear as a result of an airplane flight. She states she flies on a regular basis for her job. You diagnose this patient with barotraumas. Which of the following practices would you advise this patient to perform during an airplane flight?
3. A 44-year-old female hospital worker presents with a productive, bloody cough that has persisted for several weeks. She also complains of fever, night sweats, anorexia, and weight loss. Auscultation of the chest reveals post-tussive rales. Based on the patient’s presentation and physical examination, the most appropriate diagnosis is:
4. A 12-month-old infant presents with skull deformity and rib-breastbone joint enlargement. The child had development issues including delays in sitting, walking, and crawling. Bloodwork showed decreased calcium and vitamin D. X-ray reveals flattened skull, bowing of long bones, and dorsal kyphosis. Based on the patient’s presentation, history, and test results, which of the following is the correct diagnosis?
5. A 53-year-old male is diagnosed with aseptic necrosis of the hip. Which of the following medications would you prescribe for maintenance therapy to avoid collapse of the femoral head?
6. A 68-year-old male presents with shortness of breath, retrosternal chest pain, weakness, fatigue, ascites, and cyanosis. Physical examination reveals narrow splitting and accentuation of the second heart sound and a systolic ejection click. Chest X-ray reveals enlarged pulmonary arteries. Based on the patient’s presentation, physical examination, and test results, which of the following is the most appropriate diagnosis?
7. A 66-year-old female who has recently undergone radiation therapy for breast cancer presents with shortness of breath and reduced exercise capacity. Auscultation of the chest reveals right-sided rales. Chest X-ray shows mildly enlarged cardiac silhouette. Echocardiogram reveals mildly reduced left ventricular function. Based on the patient’s presentation, physical examination, and test results, which of the following is the most appropriate diagnosis?
8. A 36-year-old female presents with progressive hearing loss, tinnitus, and dizziness. You diagnose this patient with Meniere’s disease. Which of the following treatment options would you prescribe for treatment of this disorder?
9. An 80-year-old female presents with unexplained neck pain, scalp tenderness, headache, and vision difficulties. Her bloodwork reveals marked elevations in erythrocyte sedimentation rate and C-reactive protein. You suspect this patient is suffering from giant cell arteritis. Which of the following exams would you perform to confirm your diagnosis?
10. Which of the following medications can be administered in order to reverse the effects of an overdose of opiates?
11. A 36-year-old male presents with non-productive cough, shortness of breath, fever, and substernal discomfort. Auscultation of the chest reveals expiratory rhonchi. Chest X-ray is normal. Based on the patient’s presentation, physical examination, and test results, which of the following is the most appropriate diagnosis?
12. A 46-year-old African-American female presents with a persistent non-specific headache. Physical examination reveals her blood pressure to be 230/130 mmHg. Which of the following refers to the disorder that is characterized by blood pressure readings of this range?
13. An 80-year-old male with a history of coronarybypass graft surgery presents with abdominal pain that occurs within 30 minutes after eating. The pain only subsides after the patient lies down. Abdominal X-ray reveals colonic dilatation. Abdominal angiography was positive for chronic mesenteric ischemia. Which of the following procedures would you perform in order to correct this disorder?
14. A 32-year-old male presents, in the summer time, with a spotted tan on the face, chest, and arms. Potassium hydroxide preparation confirms the presence of hyphae and spores on the non-tanning areas of skin. Based on the patient’s presentation and test results, which of the following is the most appropriate diagnosis?
15. A 17-year-old male presents with dizziness and nausea without loss of consciousness. The patient had been active all day at a wrestling tournament. No chest X-ray abnormalities, CT scan abnormalities, or bloodwork abnormalities were detected. Which is the most appropriate diagnosis?
16. A 48-year-old male presents with productive cough, shortness of breath, fever, sore throat, headache, and body aches. Auscultation of the chest reveals expiratory rhonchi and wheezes. Chest X-ray was performed and was negative. Based on patient symptoms and physical examination, which of the following is the proper diagnosis?
17. A newborn infant presents with excessive saliva and choking with attempts to feed. Attempt to drop a nasogastric tube for feedings was unsuccessful. Based on the patient’s presentation, which of the following is the appropriate diagnosis?
18. A 22-year-old female presents to the emergency room with chest trauma, chest pain, and shortness of breath. The examination and chest X-ray reveal a tension pneumothorax. Due to the emergent nature of the situation, what is the first priority of treatment?
19. A 40-year-old female presents with muscle weakness in the pelvic girdle and generalized bone pain. She has a history of several fractures stemming from minor traumas. X-rays reveal generalized decrease in bone density with Looser zones. Bloodwork reveals vitamin D deficiency. Based on the patient’s presentation, history, and test results, the likeliest diagnosis is:
20. A 55-year-old male presents with progressive dyspnea. The patient’s history reveals he worked in a coal mine for several years. Physical examination reveals inspiratory crackles. Chest X-ray reveals small opacities in the upper lung fields. Based on the patient’s presentation, history, and test results, which of the following is the most accurate diagnosis?
21. Which of the following classes of medications has been proven successful for the treatment of fibromyalgia?
22. A 28-year-old female presents with a dark brown lesion on her neck. The lesion has an irregular border that has changed in size since her last visit. Based on the patient’s presentation alone, which of the following is the most likely diagnosis?
23. A 35-year-old male presents with early, recent onset of male pattern baldness. His area of hair loss is relatively small. Which of the following medications is the safest, most effective treatment to slow the progression of this patient’s male pattern baldness?
24. Which of the following medications is administered to enhance fetal lung maturity in premature infants?
25. A 55-year-old male presents to the emergency room in hypovolemic shock. Which of the following laboratory tests will assist in revealing the cause of shock?

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