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Pharmacology: Chemotherapy
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Pharmacology: Chemotherapy
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25 Questions

1. Gamma immunoglobulin is considered
2. Which one of the following agents is able to suppress both B and T lymphocytes via its inhibition of de novo synthesis of purines?
3. Which of the following is true of acyclovir treatment of genital herpes simplex ?
4. For radical cure of malaria the drug of choice is
5. In a patient of pulmonary tuberculosis, pyrazinamide is most active on the following subpopulation of tubercle bacilli
6. Which enzyme is used by the Human Immunodeficiency Virus (HIV) to form deoxyribonucleic acid (DNA) in the host cell?
7. Relative to Lugol’s solution propylthouracil has
8. Fluconazole differs from ketoconazole in that
9. In the management of patients with AIDS, the sulfonamides are often used in combination with inhibitors of folate reductase. However, such combinations have minimal activity against
10. Trimethoprim inhibits bacteria without affecting mammalian cells because
11. Sulphonamide-trimethoprim combination becomes bactericidal because
12. The best product to treat vulvar pruritus in a woman with a vaginal yeast infection is
13. Which of the following diarrhoeas is consistently benefited by antimicrobial therapy
14. Which one of the following drugs is recommended as a single agent for oral treatment of uncomplicated malaria due to chloroquine–resistant P falciparum strains?
15. Tinidazole differs from metronidazole in that
16. In addition to having antiamoebic activity, tinidazole inhibits
17. Glycoprotein is considered a protein linked to
18. Over 90% of this drug is excreted in the urine in intact form. Because its urinary solubility is low, patients should be well hydrated to prevent nephrotoxicity
19. Passive immunization involves
20. Drug of choice for guinea worm infestation is
21. The most important reason for using a combination of chemotherapeutic agents in the treatment of tuberculosis is
22. This agent, which is used in the chemotherapy of Hodgkin’s lymphoma, is potentially leukemogenic
23. In a patient with diffuse lymphoma, the oncologist suggests a treatment strategy that involves the initial administration of doxorubicin to obtain a significant log– kill, followed by the cell cycle–specific drugs cytarabine and vincristine. This therapeutic strategy is called
24. The fastest acting schizontocidal drug among the following is
25. The rationale for combination chemotherapy includes all of the following except