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USMLE Step 1 Pharmacology
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USMLE Step 1 Pharmacology
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25 Questions

1. What enzyme is responsible for the breakdown of ACh in the synaptic cleft?

2. Antiarrhythmic class IV- toxicity?

3. Which cancer drugs inhibit nucleotide synthesis(3)?

4. Adverse effect of Nitroprusside?

5. List the mechanism - clinical use - & toxicity of Tamoxifen.

6. What are the four conditions in Which Omeprazole - Lansoprazole is used?

7. Resistance mechanisms for Chloramphenicol

8. Which drug increases Sys BP w/o affecting Pulse Pressure

9. What is the category - mechanism of action - and effect of Ipratroprium in Asthma treatment?

10. Name the steps in drug approval(4)?

11. What are the products and their toxicities of the metabolism of Ethylene Glycol by / alcohol dehydrogenase?

12. What is the clinical use for Warfarin?

13. Which drug(s) cause this reaction: Gynecomastia (6)?

14. What should not be taken with Tetracyclines? / Why?

15. What is the category - mechanism of action - and particular use of beclomethasone and prednisone in Asthma treatment?

16. K+ sparing diuretics - clinical use?

17. How is Amphotericin B administered for fungal meningitis?

18. Cocaine shares is mechanism of action with What antidepressant

19. What is the major side effect for Ampicillin and Amoxicillin?

20. Mnemonic for Foscarnet?

21. What are three toxicities of Propylthiouracil?

22. Why are the Sulfonylureas inactive in IDDM (type -1)?

23. Isopoterenol was given to a patient with a developing AV block - why?

24. What is the clinical utility of clonidine?

25. List the specific antidote for this toxin: Tricyclic antidepressants

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