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What will be the maintenance dose of a sustained release 12 hour formulation of drug X exhibiting one compartment kinetics with a half-life of 6 hours, plasma concentration (steady state) 6 mg/ml, volume of distribution 30 L, and an oral bioavailability of 80%?

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What will be the maintenance dose of a sustained release 12 hour formulation of drug X exhibiting one compartment kinetics with a half-life of 6 hours, plasma concentration (steady state) 6 mg/ml, volume of distribution 30 L, and an oral bioavailability of 80%?






 
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