1. Atracuriumbesylate, a neuromuscular blocking agent, is metabolized through one of the following reactions. Identify that.

2. For the management of which disease the given drug tacrine is used? Identify. N NH2

3. Progesterone is obtained from diosgenin through the following sequence of chemical reactions: [P]: Acetylation, CrO3 (oxidation), acetolysis, H2/Pd, hydrolysis and Oppenauer oxidation [Q]: Oppenauer oxidation, acetylation, CrO3 (oxidation), acetolysis, H2/Pd and hydrolysis [R]: CrO3 (oxidation), acetolysis, acetylation, Oppenauer oxidation, hydrolysis and H2/Pd [S]: Acetylation, H2/Pd, hydrolysis, CrO3 (oxidation), Oppenauer oxidation and acetolysis Choose the correct sequence of reactions.

4. Given below are four statements in context of hecogenin: [P]: It is a saponin [Q]: It is useful for the semi-synthesis of steroidal drugs [R]: It is not a glycoalkaloid [S]: It is obtained from Dioscorea tubers Choose the correct combination of statements.

5. Following are some drug derivatives used to increase/ decrease the water solubility of the parent drugs: [P]: Rolitetracycline [Q]: Erythromycin lactobionate [R]: Chloramphenicol succinate [S]: Erythromycin stearate Choose the correct combination of statements.

6. Which of the following respective Phase-I and Phase-II reactions are the most common drug in biotransformation reactions?

7. Metformin causes the following actions except for the one. Identify that.

8. Which one of the following classes of drugs causes side effects like dryness of mouth, tachycardia, urinary retention, constipation, blurring of vision, precipitation of glaucoma, drowsiness and impairment of cognition?

9. Corticosteroids are administered to treat some of the given disease states: [P]: Peptic ulcer [Q]: Bronchial asthma [R]: Nephrotic syndrome [S]: Myasthenia gravis Choose the correct statement about the use of corticosteroids for the treatment of these diseases.

10. Which one of the followings is not used in preparation of baby powders?

11. Some statements are given about disodium edetate: [P]: Disodium edetate is a bidentate ligand [Q]: Disodium edetate is a complexing agent but not a chelating agent [R]: Disodium edetate can be used for the assay of lithium carbonate [S]: Disodium edetate can be used for the assay of zinc sulphate Choose the correct answer.

12. Increased risk of hypoglycemia and weight gain is the common side effect of drugs used in the management of Type-2 diabetes mellitus. Following are some commonly used drugs, alone or in combination, for the management of Type-2 diabetes mellitus: [P]: Metformin [Q]: Pioglitazone [R]: Glipizide [S]: Sitagliptin Choose the correct combination which is weight neutral and without risk of hypoglycemia.

13. Listed below are some phytoconstituents. [P]: Galactomannan [Q]: Glucomannan [R]: Barbaloin [S]: Phyllanthin Identify the constituent(s) present in Aloe vera.

14. Identify the metabolite of prontosil responsible for its antibacterial activity.

15. Choose the correct combination: (i) Rod mill (ii) Hammer mill (iii) Fluid energy mill (p) Dried plant drug (q) Thermolabile drug (r) Paint

16. Which of the following are the critical neurotransmitters playing major role in depression?

17. Read the following statements carefully about nonaqueous titrations: [P]: Acetate ion is the strongest base capable of existence in acetic acid. [Q]: Mixtures of bases of different strengths can be analyzed by selecting a differentiating solvent for the bases. [R]: Acetic acid acts as a leveling solvent for various acids like perchloric and hydrochloric acids. [S]: Mixtures of bases of different strengths can be analyzed by selecting a leveling solvent for the bases. Choose the correct answer.

18. Rhizomes of Zingiberofficinale contain some sesquiterpene hydrocarbons. Some hydrocarbons are given below: [P]: b-Bisabolene [Q]: Gingerone A [R]: Gingerol [S]: Zingiberene Identify the correct pair of constituents present in the rhizomes.

19. Which one of the following therapeutic classes has been proved clinically as a first line therapy for heart failure and has shown decreased hospitalization, improved symptoms and delayed disease progression?

20. Some of the following statements describe the properties of dropping mercury electrode (DME) correctly: [P] Constant renewal of electrode surface eliminates poisoning effects. [Q] Mercury makes many metal ions easily reducible. [R] Mercury has large hydrogen over-voltage. [S] The electrode can get oxidised with ease. Identify the correct combination of statements.

21. Out of the four given compounds choose the one which is aromatic?

22. Some statements are given for clavulanic acid, sulbactam and tazobactam: [P]: All three lack the 6-acylamino side chain [Q]: All are potent inhibitors of the enzyme b-lactamase [R]: All are prodrugs of penicillin [S]: All have weak antibacterial activity Choose the correct combination of statements.

23. For the equation PV = nRT to hold true for a gas, all of the following conditions are necessary except for one. Identify that.

24. Which of the following cytokines are the most important regulators in inflammation and are the targets for anti-inflammatory agents used in rheumatoid arthritis?

25. East's camphor method is used for determination of molecular weight of solutes which are soluble in molten camphor. The basic principle of the method is dependent on one of the following properties. Identify that.