1. East's camphor method is used for determination of molecular weight of solutes which are soluble in molten camphor. The basic principle of the method is dependent on one of the following properties. Identify that.

2. One of the following is not required for the initiation and maintenance of plant tissue culture. Identify that.

3. Corticosteroids are administered to treat some of the given disease states: [P]: Peptic ulcer [Q]: Bronchial asthma [R]: Nephrotic syndrome [S]: Myasthenia gravis Choose the correct statement about the use of corticosteroids for the treatment of these diseases.

4. Naringin, obtained from orange peel, can be named as one of the following. Identify the correct name.

5. Which one of the following drugs produces significant relaxation of both venules and arterioles?

6. Misoprostol has a cytoprotective action on gastrointestinal mucosa because of one of the following actions. Identify that.

7. What is the primary mechanism of action of local anaesthetics?

8. Both of the CMR and PMR spectra of an unknown compound show four absorption peaks each. Identify the unknown compound.

9. Given herewith are two statements: [P]: Digitoxin is a secondary glycoside from Digitalis purpurea [Q]: Digitoxin is a partially hydrolysed glycoside of purpurea glycoside A Determine the correctness of the above statements.

10. Increased risk of hypoglycemia and weight gain is the common side effect of drugs used in the management of Type-2 diabetes mellitus. Following are some commonly used drugs, alone or in combination, for the management of Type-2 diabetes mellitus: [P]: Metformin [Q]: Pioglitazone [R]: Glipizide [S]: Sitagliptin Choose the correct combination which is weight neutral and without risk of hypoglycemia.

11. Some statements are given for clavulanic acid, sulbactam and tazobactam: [P]: All three lack the 6-acylamino side chain [Q]: All are potent inhibitors of the enzyme b-lactamase [R]: All are prodrugs of penicillin [S]: All have weak antibacterial activity Choose the correct combination of statements.

12. Which one of the following anti-asthmatic drugs can cause convulsions and arrhythmia?

13. Read the following statements carefully about nonaqueous titrations: [P]: Acetate ion is the strongest base capable of existence in acetic acid. [Q]: Mixtures of bases of different strengths can be analyzed by selecting a differentiating solvent for the bases. [R]: Acetic acid acts as a leveling solvent for various acids like perchloric and hydrochloric acids. [S]: Mixtures of bases of different strengths can be analyzed by selecting a leveling solvent for the bases. Choose the correct answer.

14. Given below are four statements in context of hecogenin: [P]: It is a saponin [Q]: It is useful for the semi-synthesis of steroidal drugs [R]: It is not a glycoalkaloid [S]: It is obtained from Dioscorea tubers Choose the correct combination of statements.

15. There are some statements related to the protein binding of drugs as given below: [P]: Protein binding decreases the free drug concentration in the system. [Q]: Protein binding to plasma albumin is an irreversible process. [R]: Drugs with a low lipophilicity have a high degree of protein binding. [S]: Protein binding of one drug can be affected by the presence of other drug. Choose the correct combination of statements.

16. Parachor and Molar refraction can be categorized under one of the following properties. Identify that.

17. Read the following statements about SN1 reactions: [P]: They proceed with complete inversion (Walden inversion). [Q]: They proceed with racemization plus some net inversion. [R]: They are characterized by rearrangements. [S]: They are characterized by the reactivity sequence, CH3>1°>2°>3° Choose the correct combination.

18. Which one of the following statements is false for fluoroquinolones?

19. In amperometry, rotating platinum electrode (RPE) is used as indicating electrode. It has certain advantages as well as disadvantages. Read the following statements about the use of rotating platinum electrode in amperometry: [P]: It causes large diffusion current due to rotation resulting in greater mass transfer [Q]: It causes greatly reduced residual current due to lack of condenser effect [R]: It has a low hydrogen over potential Choose the correct combination of statements.

20. Heat sensitive materials like fruit juice are evaporated in which one of the following?

21. One of the following ring systems can be used as the bioisosteric replacement for benzene ring in drug design: [IP]: Thiophene [Q]: Cyclohexa-1,3-diene [R]: Pyrrolidine [S]: Imidazoline Identify the correct answer.

22. Identify the group of enzymes that utilizes NADP or NAD as coenzymes and catalyses biochemical reactions by the transfer of electrons from one molecule to another.

23. Which one of the following properties is characteristic of microemulsions?

24. Which one of the followings would be an offence in accordance with the provisions of the Drugs and Cosmetics Act, 1940?

25. Which one of the following therapeutic classes has been proved clinically as a first line therapy for heart failure and has shown decreased hospitalization, improved symptoms and delayed disease progression?