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AA sequences (4-8) rich in lysine, arginine, proline- essential component of proteins bound for or residing in nucleus (eg histones)- ribosomal subunits / mRNA made in nucleus, then exported- nuclear pores (envelope) recognize these signals + transport proteins into nucleus via ATPase- mutation in a single AA may prevent nuclear transport

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Self Assessment and Review of Anatomy.


1. AA sequences (4-8) rich in lysine, arginine, proline

- essential component of proteins bound for or residing in nucleus (eg histones)
- ribosomal subunits / mRNA made in nucleus, then exported

- nuclear pores (envelope) recognize these signals + transport proteins into nucleus via ATPase

- mutation in a single AA may prevent nuclear transport





 
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