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In acute inflammation, what causes an ↑ in intercellular pore size, hence ↑ permeability of vessels with a consequent outpouring of protein- and electrolyte-rich intravascular fluid into the instertitium?

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1. In acute inflammation, what causes an ↑ in intercellular pore size, hence ↑ permeability of vessels with a consequent outpouring of protein- and electrolyte-rich intravascular fluid into the instertitium?





 
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