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Affects males & females equally - Manifests in heterozygous state - Can be transmitted by either parent - Often delayed onset (adult dx) - Vertical transmission - New mutations occur in germ cells of older fathers - Can exhibit reduced penetrance & v

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1. Affects males & females equally - Manifests in heterozygous state - Can be transmitted by either parent - Often delayed onset (adult dx) - Vertical transmission - New mutations occur in germ cells of older fathers - Can exhibit reduced penetrance & v





 
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