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Molecular Biology Practice Test: Genomes and DNA
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Genomes and DNA topics include: Genome organization, eukaryotic dna features, palindromes, inverted repeats and stem and loop structures, dna fragments separation by electrophoresis, dna helical structures, dna topology, chromatin centromere and telomere. A genome is an organism's complete set of DNA instructions. It contains all the information needed for an individual to develop and function.  The genome is made up of DNA, a long two-stranded chemical polymer. Each DNA strand is made up of four different units, called nucleotides, that are linked end to end to form a long chain.  Most... Show more
Molecular Biology Practice Test: Genomes and DNA
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25 Questions

1. The active site of the topoisomerase contains a tyrosine residue.
2. Which of the following is not a property of topoisomerase?
3. Agarose can be extracted from which of the following?
4. With respect to remodeling complex of nucleosome, which of the following is not true?
5. Which of the following is not promoted by histone tail modification?
6. Interwound writhe and spiral writhe are topologically different.
7. The promotion of DNA breaking and rejoining by topoisomerase requires______________
8. With respect to microsatellite DNA which of the following is correct?
9. The nucleosome is seen to have negative supercoils.
10. The histone tails stabilize the 30 nm fibre by interacting with adjacent nucleosomes.
11. The unpacked stretches of DNA are the extra chromosomal load found in the eukaryotic genome.
12. Inverted repeat have a number of biological functions. Which of the following is a biological function of an inverted repeat?
13. The fluorescent dye such Ethidium is used for visualizing DNA. How do ethidium binds to DNA?
14. Plectonomic writhe is __________
15. Genome – wide repeat unit are generally transposable elements.
16. Nucleosome is made up of __________
17. Which of the following histone pairs forms tetramers in solution?
18. Which of the following regions promote histone – DNA association?
19. Strand separation is easily accomplished in positively supercoiled DNA.
20. Which of the following is not a character of B form of DNA?
21. Double-stranded structure of nucleic acid is the basic requirement for palindromic sequences.
22. Pulse field gel electrophoresis separates DNA molecules of size ___________
23. Which of the following will form a palindromic sequence?
24. Type I topoisomerase can never decatenate catenated circular DNA?
25. With respect to the “tails” of the histone molecules which of the following is not true?