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Molecular Biology Practice Test: Genomes and DNA
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Genomes and DNA topics include: Genome organization, eukaryotic dna features, palindromes, inverted repeats and stem and loop structures, dna fragments separation by electrophoresis, dna helical structures, dna topology, chromatin centromere and telomere. A genome is an organism's complete set of DNA instructions. It contains all the information needed for an individual to develop and function.  The genome is made up of DNA, a long two-stranded chemical polymer. Each DNA strand is made up of four different units, called nucleotides, that are linked end to end to form a long chain.  Most... Show more
Molecular Biology Practice Test: Genomes and DNA
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25 Questions

1. How is the extent of supercoiling measured?
2. Nucleosome was first described in 1974 by ___________
3. Which of the following regions promote histone – DNA association?
4. With respect to the solenoid model of nucleosome, which of the following is true?
5. What marks the difference between the solenoid and the zig-zag models of 30 nm fibres?
6. Which of the following is an example of an inverted repeat?
7. Association of DNA and histone is mediated by _________
8. Linking number is always a ___________
9. In higher salt concentration the DNA helix assumes the right-handed conformation.
10. Histone H1 binds two DNA helices.
11. At which phase do transcription ceases?
12. Nucleosome is made up of __________
13. How many contacts are observed between the DNA and the histone core protein?
14. Type I topoisomerase can never decatenate catenated circular DNA?
15. Which of the following is a function of a modified histone tail?
16. Which of the following is not true about positive supercoils?
17. 3 – dimension structure of cccDNA is ___________
18. Agarose can be extracted from which of the following?
19. Pulse field gel electrophoresis separates DNA molecules of size ___________
20. In the beads on a string model, the bead is made up of __________
21. Which of these factors contribute to a decrease in gene density?
22. Which of the following does not occur during cell division in prokaryotes?
23. What is the minimum number of bases required for loop stability?
24. Which of the following is not a character of polyacrylamide gel?
25. Strand separation is easily accomplished in positively supercoiled DNA.