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Sepsis and anaphylaxis (along with the obvious hemorrhaging) reduce circulating volume by way of increased capillary permeability - which leads to reduced preload (volume in the left ventricle at the end of diastole). This is a toughie...think about

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1. Sepsis and anaphylaxis (along with the obvious hemorrhaging) reduce circulating volume by way of increased capillary permeability - which leads to reduced preload (volume in the left ventricle at the end of diastole). This is a toughie...think about





 
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