Wherever there is a hormone secretory function, there is going to be some loosening of the blood-brain barrier, that is to say the ______ junctions between the brain capillary endothelial cell and surrounding ________s are not present. And so, that's important, for example, at the base of the fore brain, where we find the ______thalamus. Where there are neurons that are secreting peptides into the blood that will affect the anterior pituitary. There are other places in the brain, such as in the ______ gland, where hormones such as melatonin are secreted and enter the blood stream.