An acetoacetic ester synthesis of a ketone proceeds by alkylation of the enolate of the acetoacetic ester followed by ester hydrolysis and decarboxylation of the β-ketoacid. Which of the following methyl ketones is difficult to prepare by this method?

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Organic Compounds topics include: Preparation and reactions of alcohols, phenols, ethers, oxiranes, glycols, glycerol, aldehydes, ketones, benzaldehyde. aldehydes, tautomerism, physical and chemical properties of carboxylic acids, aldehydes, ketones, acid chlorides and anhydrides, amides, esters, saponification, claisen and cross claisen condensation. Here are some organic compounds that contain oxygen: Organic peroxides: Contain two oxygen atoms that are joined together. They are used as bleaching agents and to start a process called polymerization that creates plastic polymers. However,... Show more

An acetoacetic ester synthesis of a ketone proceeds by alkylation of the enolate of the acetoacetic ester followed by ester hydrolysis and decarboxylation of the β-ketoacid. Which of the following methyl ketones is difficult to prepare by this method?






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