An 8-year-old female presents with edema of the cutaneous and mucosal tissue layers. Her mother reports that the condition is recurrent and seems to occur more often during stressful situations. The child is diagnosed with hereditary angioedema. Which of the following is deficient in this child?

Innate immune responses trigger inflammation to help the body fight pathogens and facilitate wound repair. Inflammation is typically characterized by pain, heat, redness, and/or swelling of the area of the body where the inflammatory response is activated.  In the early stages of normal wound healing, innate immune cells produce proinflammatory cytokines that: Induce antimicrobial molecules, Attract leukocytes, and Create an environment to protect from microbial infection.  Proper inflammatory responses provide broad spectrum protection against infections and orchestrate long-term adaptive... Show more

Innate immune responses trigger inflammation to help the body fight pathogens and facilitate wound repair. Inflammation is typically characterized by pain, heat, redness, and/or swelling of the area of the body where the inflammatory response is activated. 

In the early stages of normal wound healing, innate immune cells produce proinflammatory cytokines that: Induce antimicrobial molecules, Attract leukocytes, and Create an environment to protect from microbial infection. 
Proper inflammatory responses provide broad spectrum protection against infections and orchestrate long-term adaptive immunity toward specific pathogens. However, impaired or excessive innate immune responses can promote nonhealing wounds. 

The three phases of wound healing are:

Inflammatory phase: This phase begins at the time of injury and lasts up to four days.
Proliferative phase: This phase begins about three days after injury and overlaps with the inflammatory phase.
Remodeling phase: This phase can continue for six months to one year after injury.

Show less