Innate immune responses trigger inflammation to help the body fight pathogens and facilitate wound repair. Inflammation is typically characterized by pain, heat, redness, and/or swelling of the area of the body where the inflammatory response is activated.  In the early stages of normal wound healing, innate immune cells produce proinflammatory cytokines that: Induce antimicrobial molecules, Attract leukocytes, and Create an environment to protect from microbial infection.  Proper inflammatory responses provide broad spectrum protection against infections and orchestrate long-term adaptive... Show more

Innate immune responses trigger inflammation to help the body fight pathogens and facilitate wound repair. Inflammation is typically characterized by pain, heat, redness, and/or swelling of the area of the body where the inflammatory response is activated. 

In the early stages of normal wound healing, innate immune cells produce proinflammatory cytokines that: Induce antimicrobial molecules, Attract leukocytes, and Create an environment to protect from microbial infection. 
Proper inflammatory responses provide broad spectrum protection against infections and orchestrate long-term adaptive immunity toward specific pathogens. However, impaired or excessive innate immune responses can promote nonhealing wounds. 

The three phases of wound healing are:

Inflammatory phase: This phase begins at the time of injury and lasts up to four days.
Proliferative phase: This phase begins about three days after injury and overlaps with the inflammatory phase.
Remodeling phase: This phase can continue for six months to one year after injury.

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