Pharmacology: Match The Following (Solved)

MATCH THE FOLLOWING     

Match the correct mechanism of action for the diuretic agents mentioned below:
(1)  Acetazolamide (a) Increases serum K+ level (2) Chlorthiazide (b) Competitively antagonizes aldodsterone (3) Spiranolactone (c) Inhibits active Na+ secretion, decreasing K+ excretion in the distal nephron (4) Triamterene (d) Inhibits carbonic anhydrase (e) Inhibits electrolyte reabsorption in the distal portion of the ascending limb of the loop of Henle
Answer: 1-d, 2-e, 3-b, 4-c 

Listed are some of the commonly used drugs. Their pharmacological actions are listed in A to E, match them.
(1)  Aspirin (a) Rises body temperature (2) Acetaminophen (b) Non–analgesic anti-inflammatory (3) Phenylbutazone (c) Non–anti-inflammatory analgesic (4) Probenacid (d) Increases of depth of respiration (e) Increases fluid retention
Answer: 1-d, 2-c, 3-b, 4-e 

The following are the test animals or substances used for the biological assay of preparations listed in A to E. Match them correctly.
(1)  Mice (a) Vasopressin (2) Albino rats (b) Diphtheria antitoxin (3) Guinea pigs (c) Insulin (4) Sheep plasma (d) Human antihaemophyllic fraction
Answer: 1-c, 2-d, 3-a, 4-c

The drug A to E are used as diuretics. Match them to their classes.
(1)  Osmotic diuretic (a) Spiranolactone (2) Loop diuretic (b) Isosorbide (3) Potassium sparing (c) Merasalyl theophylline diuretic (d) Furosemide (4) Organomercurial (e) Probenecid diuretic
Answer: 1-b, 2-d, 3-a, 4-c 

Pharmacologicla activity of certain well known plant drugs are listed A to E. Match them.
(1)  Papaverin (a) Weak analeptic (2) Camphor (b) Vasodilator (3) Veratrum alkaloids (c) Antineoplastic (4) Vincristine (d) Central vasoconstrictor (e) Anxiolytic
Answer: 1- b, 2-a, 3-b, 4-c 

Listed are drugs 1 to 4. Their appropriate antihypertensive mechanisms are given in A to F match them.
(1)  Pindalol (a) Vadoilator (2) Minoxidil (b) Angiotiensin coverting enzyme inhibitor (3) Captopril (c) Diuretic (4) Amiloride (d) Beta–blocker (e) Centrally acting alpha adrenoceptor agonist f) Potassium induction
Answer: 1-d, 2-a, 3-b, 4c

Symptoms for the following diseases are indicated from A to E . Match them.
(1)  Cushing’s syndrome (a) Hyperthyroidism (2) Addison’s disease (b) Inflammatory bowel (3) Grave’s disease (c) Decreased production of cortisol (4) Crohn’s disease (d) Decreased production of cortisol (e) Increased production of cortisol
Answer: 1- e, 2-c, 3-a, 4-b 

The undersirable effects of the antibiotics are listed in A to E. Match them.
(1)  Tetracycline (a) Gray–baby syndrome (2) Streptomycin (b) Discolouration of teeth (3) Chloramphenicol (c) Jaundice (4) Rifampicin (d) Obesity
Answer: 1-b, 2-e, 3-a, 4-c 

Match the following terms with their respective definitions A to E:
(1)  Achyliagestrica (a) Decrease in alkali contents (2) Acidosis (b) Absence of hydrochloric acid (3) Actinomycosis (c) A deficient disorder of adrenal contex with anaemia, weakness, dyspepsia, hypotension (4) Addision’s disease (d) A fungal disease caused by Actinomyces (e) A state of psychic and physical drug dependence
Answer: 1-b, 2-a, 3-d, 4-c

Match the following categories of Adrenocorticosteroids with their respective examples A to E:
(1)  Glucocorticoids (a) Aldosterone, Fludrocortisone (2) Mineral corticoids (b) Ketokonazole, Metyapone (3) Receptor (c) Cholesterol, β-Sitosterol (4) Synthetic Inhibitors (d) Cortisol, Triamcinolone (e) Mifepristone, Spironolactone
Answer: 1-d, 2-a, 3-e, 4-b 

Match the following anaesthetics with their respective nature A to E:
(1)  Coacine (a) Other anaesthetic (2) Lignocaine (b) Synthetic non-nitrogenous compound (3) Propanediol (c) Inhaled anaesthetic (4) Chlorpromazine (d) Synthetic nitrogenous compound (e) Natural alkaloid
Answer: 1-c, 2-e, 3-d, 4-b 

Match the following antiemetic drugs with their respective categories A to E:
(1)  Weak agonist (a) Pentazocine (2) Strong agonist (b) Propoxyphene (3) Antidiarrhea (c) Heroin (4) Antitussive (d) Diphenoxylate (e) Codeine
Answer: 1-b, 2-c, 3-d, 4-e

Match the following antiarrhythmic drugs to the respective categories A to E:
(1)  Acebutalol (a) Calcium channel blocker (2) Verapamil (b) Potassium channel blocker (3) Kromakalem (c) Sodium channel blocker (4) Phenytoin (d) Beta adrenoceptor blocker (e) Chloride channel blocker
Answer: 1-d, 2-c, 3-e, 4-a 

Match the following categories of antibiotics with their respective examples A to E:
(1)  Narrow spectrum (a) Neomycin (2) Broad - spectrum (b) Cephalsporins (3) Acting on cell (c) Streptomycin membrane (4) Inhibiting protein (d) Cycloserine synthesis
Answer: 1-d, 2-a, 3-b, 4-c 

Match the following penicillins with their respective categories A to E:
(1)  Penicillin G (a) Broad spectrum (2) Penicillin V (b) Penicillinase resistant (3) Methicillin (c) Natural (4) Ampicillin (d) Semi–synthetic (e) Anti–pseudomonas
Answer: 1-c, 2-d, 3-b, 4-a

Match the following categories of anticancer hormones with their respective examples A to E:
(1)  Androgens (a) Methoxyestradiol (2) Gonadotropin- (b) Prednisolone releasing (3) Estrogens (c) Testosterone (4) Adrenocortrocoids (d) Goserelin (e) Diethylstilbestrol
Answer: 1-c, 2-d, 3-e, 4-b 

Match the following antidepressant drugs with their respective categories A to E:
(1)  Amitriptyline (a) Non-specific (2) Nizoxetin (b) Tricyclic first generation (3) Caffeine (c) Tricyclic second generation (4) Isoniazid (d) Psychomotor stimulant (e) Heterocyclic
Answer: 1-b, 2-c, 3-d, 4-a 

Match the following antidiabetic drugs with their respective categories A to E
(1)  Phenformin (a) Long acting (2) Tolbutamide (b) Rapid acting (3) NPH Insulin (c) Intermediate acting (4) Protamine zinc (d) Beguanide suspension insulin (e) Sulphonylurea
Answer: 1-d, 2-e, 3-c, 4-a

Match the following categories of antifungal drugs with their respective examples A to E:
(1)  For superficial (a) Amphotericin B infection (2) Topical (b) Nystatin (3) For systemic (c) Undercylenic acid mycoses (4) For vaginal (d) Grisefulvin candidiasis meanings (e) Nystatin
Answer: 1-d, 2-e, 3-a, 4-b 

Match the following antihyperlipidemic drugs with their respective categories A to E:
(1)  Cholesteryl amine (a) Fibric acid derivative (2) Clofibrate (b) Bile acid sesquestrant (3) Lovastation (c) VLDL secreting inhibitor (4) Niacin (d) Antioxidant (e) HMGCO – A reductase
Answer: 1-b, 2-a, 3-e, 4-c 

Match the following categories of antimalarial drugs with their respective examples A to E:
(1)  Acridine dyes (a) Biguanide (2) Cinchona alkaloid (b) Primaquine (3) Aminoquinoline (c) Quinacrine (4) Diaminopyrimidine (d) Quinine (e) Mepacrine
Answer: 1-e, 2-d, 3-b, 4-c

Match the following antiseptic drugs with their respective categories A to E:
(1)  Halazone (a) Dye (2) Thimerosol (b) Anionic surfactant (3) Delqualinium (c) Halogen containing (4) Proflavin (d) Heavy metals (e) Cationic surfactant
Answer: 1-c, 2-d, 3-e, 4-a 

Match the following terms with their respective meaning A to E:
(1)  Aphrodisiac (a) Pain in joint (2) Arrhythmia (b) Loss of power of governing (3) Arthralgia (c) Absence of spermatozoa in the sperm (4) Ataxia (d) Exciting sexual desire (e) Variation from the normal regular rhythm of the heart beat
Answer: 1-d, 2-e, 3-a, 4-b 

Match the following antiasthamtic drugs with their respective categories A to E:
(1)  Ephedrine (a) Purine base bronchodilator (2) Theophyline (b) Symathomimetic bronchodilator (3) Ipratropium bromide (c) Polypetide (4) Disodium (d) Anticholinergics bronchodilator cromoglycate (e) Anti - inflammatory
Answer: 1-b, 2-a, 3-d, 4-e

Match the following terms with their respective meaning A to E:
(1)  Bradicardia (a) Irritation of the mucous membrane (2) Bronchitis (b) Feeble state produced by a serious disease (3) Chachexia (c) Inflammation of mucous membrane (4) Catarrh (d) Glowness of the heart beat (e) Narrowing of the bronchi
Answer: 1-d, 2-c, 3- b, 4- a 

Match the following drugs with therir respective mechanisms A to E:
(1)  Methotrexate (a) Nucleic acid derivative binding to viral enzymes (2) PAS (b) Inhibitor of dihydrofolate reductase (3) Acyclovir (c) Competitive inhibition of PABA uptake (4) Rifumpicin (d) Reversible inhibition of protein synthesis (e) Inhibition of DNA dependent RNA polymerase
Answer: 1-b, 2-c, 3-a, 4-e 

Match the following cholinoceptor acting drugs their categories A to E:
(1)  Pilocarpine (a) Nicotinic blockers (2) Physostigmine (b) Cholinesterase regenerator (3) Pirenzepine (c) Direct acting agonist (4) Pralidoxine (d) Indirect acting carbamate (e) Muscarinic blocker
Answer: 1-c, 2-d, 3-e, 4-b

Match the following diseases with their respective diagnostic tests A to E:
(1)  Leprosy (a) Shick test (2) Scarlet Fever (b) Lepromin Test (3) Syphilis (c) Dick test (4) Typhoid (d) VDRL and Widal test (e) Widal test
Answer: 1-b, 2-c, 3-d, 4-e 

Match the following drugs with their respective mechanisms of action from A to E:
(1)  Local anaesthetics (a) Blocks calcium channels (2) Minoxidil (b) Prevents synthesis of prothrombin (3) Proserpine (c) Blocks neuronal sodium channels (4) Warfarin (d) Vasodilation by blocking potassium channels (e) Depletes the catecholamine store in neurons
Answer: 1-c, 2-d, 3-e, 4-b 

Match the following drugs of abuse with their respective categories A to E:
(1)  Scopolamine (a) Inhalant (2) Nitrous oxide (b) Marijuana (3) Hashish (c) Hallucinogen (4) Cocaine (d) Sedative hyponotic (e) Stimulant
Answer: 1-c, 2-a, 3-b, 4-e

Match the following enzymes inhibited by the corresponding agents A to E:
(1)  Acetylcholine (a) Acetazolamide esterase (2) Carbonic anhydrase (b) Methotrexate (3) Dihydrofoleate (c) Trimethoprim reducatase in human (4) Dihydrofoleate (d) Physostigmine reducatase in microbes (e) Primethamine
Answer: 1-d, 2-a, 3-b, 4-c 

Match the following neurotransmitters with their respective localizations A to E:
(1)  GABA (a) Neuromuscular junction (2) L - Glutamate (b) Hypothalamus (3) Neuropeptide (c) Substantia nigra and striatum (4) Dopamine (d) Cerebral cortex (e) Cerebral nerve
Answer: 1-e, 2-d, 3-b, 4-c 

Match the following drugs used in Parkinsonism with their respective categories A to E:
(1)  Levodopa (a) Dopa decarboxylase inhibitor (2) Carbidopa (b) MAU inhibitor (3) Biperiden (c) Used in Wilson’s disease (4) Penicillamine (d) Dopamine prodrug (e) Used in Tremor
Answer: 1-d, 2-a, 3-b, 4-c

Match the following drugs with their respective usual doses A to E:
(1)  Astemizole (a) 500 mg (2) Captopril (b) 200 mg (3) Ascorbic acid (c) 2 g (4) Cephalothin (d) 10 mg (e) 100 mg
Answer: 1-d, 2-e, 3-a, 4-c 

Match the following psychoactive drugs with their respective categories A to E:
(1)  Haloperidol (a) Leukotriene (2) Meprobamate (b) Antipsychotic (3) Imipramine (c) Anti - anxiety (4) LSD (d) Anti - depressant (e) Psychotogenic
Answer: 1-b, 2-c, 3-d, 4-e 

Match the following sympathomimetic drugs with their respective categories A to E:
(1)  Amphetamine (a) Dopamine (2) Phenylephrine (b) Indirect releaser (3) Dobutamine (c) Alpha–1 selective (4) Albuterol (d) Beta–1 selective (e) Beta–2 selective
Answer: 1-b, 2-c, 3-d, 4-e

Given below are the ailments and the drugs used. Match them correctly.
(1)  Parkinson’s disease (a) Probenecid (2) Glaucoma (b) Ampicillin (3) Gout (c) Nitroglycerin (4) Angina (d) Pilocarpine (e) Levo dopa
Answer: 1-e, 2-d, 3-a, 4-c 

Given below are the drugs and their antagonists. Match them correctly.
(1)  5–HT (a) Bemegride (2) Codeine (b) Atropine (3) Phenobarbitone (c) Cyproheptadine (4) Muscarine (d) Naloxone (e) Pyridoxine
Answer: 1-c, 2-d, 3-a, 4-b 

Choose the most appropriate from the group below to match drugs:
(1)  Cocaine (a) Central stimulant (2) Codeine (b) Acetylcholine estrase inhibitor (3) Physostigmine (c) Cardiotonic (4) Atropine (d) Relief of mild pain (e) Mydriatic
Answer: 1-a, 2-d, 3-b, 4-e

Given below are some of the drugs and their mode of action in A to E. Match them correctly.

1) Hydralazine (a) Vasodilator by direct action (2) Phenothiazine (b) Inhibits the vasconstrictor and pressor effects of 5-HT (3) Methysergide (c) Antagonist to HT receptor of Histamine (4) Tolazamide (d) Stimulate the islet tissue to secrete insulin (e) Inhibiting the enzyme carbonic anhydrase
Answer: 1-a, 2-a, 3-a, 4-a 

Givern below are the hypotensive agents. Match their modes of action:
(1)  Minoxidil (a) Alpha adereno receptor antagonist (2) Parazosin (b) Beta adereno receptor antagonist (3) Alpha – methyl dopa (c) From alpha methyl norepinepherine (4) Clonidine (d) Direct action on blood vessel (e) Decreases sympathetic activity through brain
Answer: 1-b, 2-a, 3-a, 4-e 

Given below are the drugs and their enzymes inhibited by them. Match them correctly.
(1)  Physostigmine (a) COMT (2) Imipramine (b) Acetaldehyde dehydrogenase (3) Pyrogallol (c) Carbonic anhydrase (4) Disulfiram (d) Cholinesterase (e) MAO
Answer: 1-e, 2-d, 3-b, 4-c

Choose the most appropriate drug for the following:
(1)  Potassium sparing (a) Spironolactone diuretic (2) Loop diuretic (b) Mannitol (3) Osmotic diuretic (c) Furosemide (4) Carbonic anhydrase (d) Acetazolamide inhibitor (e) Aldosterone
Answer: 1-a, 2-c, 3-b, 4-d 

Match the following regions in GIT with the pH levels indicated from A to E:
(1)  Mouth (a) = 5.0–6.0 (2) Stomach (b) = 6.8–7.5 (3) Deodenum (c) = 6.8–7.0 (4) Large intestine (d) = 3.0–5.0 (e) = 1.5–3.0
Answer: 1-b, 2-e, 3-d, 4-c 

For the drugs listed 1 to 4, mechanism of action is indicated from A to E. Match them:
(1)  Vincristine (a) Macrolide antibiotic which inhibits DNA dependent RNA polymerase (2) Streptomycin (b) An antibiotic cotaining nitro group which binds to 50 S ribosomal subunit (3) Chloramphenicol (c) A dimeric indole alkaloid which binds avidily to tubulin, a class of protein that forms the miotic spindle (4) Rifampicin (d) A quinoline alkalid which inhibits the growth of Plasmodium vivax (e) A naphthalene antibiotic which inhibits cell wall synthesis
Answer: 1-c, 2-d, 3-b, 4-a

For the following drugs, specific mechanism of action is given in A to D. Match them:
(1)  Spironolactone (a) Non-competitively inhibit the enzyme carbonic anhydrase (2) Acetazolamide (b) Inhibit the cotransport of Na+ and Cl- in loop of Henle (c) Competitive inhibitor of aldosterone at the receptors in the distal tubule (d) Direct inhibition of Na+ and Clreabsorption
Answer: 1-X, 2-X, 3-X, 4-X 

Match the following terms with their respective definitions A to E:
(1)  Drug allergy (a) Excessive pharmacological action of the drug due to overdosage or prolonged use (2) Toxic effect (b) Characteristic toxic effects of a drug in an individual at therapeutic doses (3) Idiosyncrasy (c) An immunologically mediated reaction producing sterotype symptoms (4) Intolerance (d) Abnormal reactivity to a chemical (e) Alteration of mood and feelings
Answer: 1-c, 2-a, 3-d, 4-b 

Match the following terms with their respective meanings A to E:
(1)  Carcinogenicity (a) Drugs causing genetic defects (2) Mutagenicity (b) Drugs causing foetal absormalities (3) Teratogenicity (c) Drugs capable of altering mood and feelings (4) Drug dependence (d) Drugs causing functional disturbances which persist, even after the offending drug (e) Drug causing cancer
Answer: 1-e, 2-a, 3-b, 4-c

Match the following teratogenic drugs and their respective produced abnormalies A to D:
(1)  Aspirin (a) Nose, eye and hand defects, growth retardation (2) Antithyroid drugs (b) Hypoplastic phalanges, cleft lip, micro-cephaly (3) Phenytoin (c) Premature closure of ductus arteriosus (4) Warfarin (d) Foetal goiter and hypothyroidism
Answer: 1-c, 2-a, 3-b, 4-a 

Match the following drugs and their respective resulted diseases A to E:
(1)  Isoniazid (a) Peptic ulcers (2) Phenothiazines (b) Hepatitis (3) Salicylates (c) Parkinsonism (4) Tetracyclines (d) Phocomelia, multiple defects (e) Discoloured and deformed teeth, retarded bone growth
Answer: 1-b, 2-c, 3-a, 4-e 

Match the following oral hypoglycaemic drugs with their respective features A to E
(1)  Tolbutamide (a) Potent (2) Penicillin V (b) Penicillinase resistant (3) Methicillin (c) Natural (4) Ampicillin (d) Semi–synthetic (e) Anti–pseudomonas
Answer: 1-e, 2-c, 3-b, 4-a

Match the following sulfonamides with their duration of actions from A to E
(1)  Sulphadiazine (a) Long acting (2) Sulfadimethoxine (b) Toxic (3) Sulfaphenazole (c) Short acting (4) Succinyl (d) Intermediate acting sulfathiazole (e) Poorly absorbed
Answer: 1-c, 2-a, 3-d, 4-e 

Match the following modes of action with their respective antimicrobial drugs A to E
(1)  Interfere with (a) Rifampicin, Norfloxacin, intermediary meta- Metronidazole bolism (2) Interfere with DNA (b) Penicillins, Cephalosporins, synthesis Vancomycin Bactracin (3) Intefere with DNA (c) Idoxuridine, Acylovir, Zidovudin (4) Inhibit cell wall (d) Sulfonamides, PAS, Ethambutol synthesis (e) Polymyxins, Colistins, Bacitracin
Answer: 1-d, 2-c, 3-a, 4-b 

Match the following categories with their respective antimicrobial drugs A to E:
(1)  Aminoglycosides (a) Polymyxin–B Colistin, Bacitracin (2) Macrolide (b) Streptomycin, Gentamycin, antibiotics Neomycin (3) Polypeptide (c) Erythromycin, Oleandomycin, antibiotics Roxi-thromycin (4) Nitrofuran (d) Vancomycin, Lincomycin, derivatives Viomycin (e) Nitrofurantoin, Furazolidone
Answer: 1-b, 2-c, 3-a, 4-e

Match the following categories of antimicrobial agents with their respective examples A to E:
(1)  Antibacterial (a) Chloroquine, Metronidazole, Diloxanide (2) Antifungal (b) Sodium fusidate, Thiacetazone (3) Antiviral (c) (Acyclovir), Amantadine, Idoxuridine, Zidovudin (4) Antiprotozoal (d) Amphotericin B, Griseofulvin, Ketoconazole (e) Aminoglycosides, Erythromycin, Penicillins
Answer: 1-e, 2-d, 3-c, 4-a 

Match the following categories of laxatives/purgati es with their respective examples A to E:
(1)  Bulk forming (a) Docusates (2) Stimulant (b) Magnesium and sodium salts (3) Osmotic (c) Bisacodyl, Senna, Castor Oil (4) Stool sofener (d) Dietary fibre, Psyllium Methylcellulose (e) Liquid paraffin
Answer: 1-d, 2-a, 3-b, 4-a 

Match the following categories of antiulcer drugs with their respective examples A to E:
(1)  Ulcer heating drugs (a) Sodium bicarbonate, sodium citrate (2) Ulcer protective (b) Carbenoxolone sodium, Deglycyrrhi-zinized liquorice (3) H2 antihistamines (c) Sucralfate, colloidal bismuth subctirate (4) Anticholinergics (d) Atropine Pirenzepine Trimipramine (e) Cimetidine, Ranitiding, Roxatidine
Answer: 1-b, 2-c, 3-e, 4-d

Match the following fat-soluble vitamins with their respective chemical constituents A to E:
(1)  Vitamin A (a) Pyridoxine (2) Vitamin D (b) Methyl Phytyl naphthaquinone (3) Vitamin E (c) Alpha tocopherol (4) Vitamin K (d) Calciferol (e) Retinol
Answer: 1-e, 2-d, 3-c, 4-b