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General Pharmacology Knowledge
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General Pharmacology Knowledge
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25 Questions

1. Which of the following salts forms an aqueous solution that is alkaline to litmus?
2. All of the following carbohydrates are considered to be polysaccharides except
3. The renal clearance of insulin is used as a measurement of
4. Bio-transformation of the drugs is to render them
5. The chances of foetal malformation with a teratogenic drug is maximum
6. Drugs interact with their receptors sites by forming
7. A drug which is generally administered in standard doses without the need for dose individualization is
8. The most vulnerable period of pregnancy for the causation of foetal malformations due to drugs is
9. The pharmacokinetic alternations in elderly are due to
10. Animal testing of potential new therapeutic agents
11. Which of the following factors is associated with an increased risk of noncompliance in the elderly?
12. Which of the following radionuclides is generator produced?
13. Which of the following agents is a prodrug that is much less toxic in mammals than in insects ?
14. ‘Drug efficacy’ refers to
15. Which of the following endogenous compounds undergo methylation ?
16. Which one of the following is a Phase II – Drug metabolizing reaction
17. Pharmacodynamic tolerance may involve changes in _____of drug receptors
18. Following compartment constitutes the largest percentage
19. The excretion of a weakly acidic drug generally is more rapid in alkaline urine than in acidic urine. This process occurs because
20. Alcohol is rapidly absorbed from the intestine because
21. Cimetidine potentiates the action of propranol, theophylline, warfarin and phenytoin because
22. In presence of competitive antagonist
23. The 'dominant lethal' test involves the treatment of a male adult animal with a chemical before mating; the pregnant female is later examined for fetal death and abnormalities. The dominant lethal test therefore is a test of
24. Following statement is true regarding therapeutic index
25. The microsomal oxidation of drugs is carried out through a larger or smaller extent in

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