Which of the following antimalarial drugs causes a dose–dependent toxic state that includes flushed and sweaty skin, dizziness, nausea, diarrhea, tinnitus, blurred vision, and impaired hearing?

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Which of the following antimalarial drugs causes a dose–dependent toxic state that includes flushed and sweaty skin, dizziness, nausea, diarrhea, tinnitus, blurred vision, and impaired hearing?