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This agent is the drug of choice in severe amebic disease and for hepatic abscess. It is activated to toxic intermediates by the pyruvate – ferredoxin oxidoreductase enzyme system present in the parasite.

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This agent is the drug of choice in severe amebic disease and for hepatic abscess. It is activated to toxic intermediates by the pyruvate – ferredoxin oxidoreductase enzyme system present in the parasite.






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