A 40-year-old female presents with muscle weakness in the pelvic girdle and generalized bone pain. She has a history of several fractures stemming from minor traumas. X-rays reveal generalized decrease in bone density with Looser zones. Bloodwork reveals vitamin D deficiency. Based on the patient’s presentation, history, and test results, the likeliest diagnosis is:

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The material on the PANCE and PANRE is organized by the NCCPA into two dimensions, as indicated in the content blueprint for the examination. - Organ systems and the diseases, disorders and medical assessments physician assistants encounter within those systems; and - The knowledge and skills physician assistants should exhibit when confronted with those diseases, disorders and assessments. Medical Content Categories % Allocation: Cardiovascular System 13% Dermatologic System 5% Endocrine System 7% Eyes, Ears, Nose, and Throat 7% Gastrointestinal System/Nutrition 9% Genitourinary... Show more

A 40-year-old female presents with muscle weakness in the pelvic girdle and generalized bone pain. She has a history of several fractures stemming from minor traumas. X-rays reveal generalized decrease in bone density with Looser zones. Bloodwork reveals vitamin D deficiency. Based on the patient’s presentation, history, and test results, the likeliest diagnosis is: