A 55-year-old male presents with headache, dizziness, weakness, fatigue, and blurred vision. Physical examination reveals systolic hypertension, engorged retinal veins, and splenomegaly. Bloodwork reveals hematocrit of 57%, elevated red cell mass, neutrophilic leukocytosis, increased basophils and eosinophils, and increased numbers of large, bizarre platelets. Based on the patient’s presentation, physical examination, and lab results, which of the following is the most appropriate diagnosis?

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The material on the PANCE and PANRE is organized by the NCCPA into two dimensions, as indicated in the content blueprint for the examination. - Organ systems and the diseases, disorders and medical assessments physician assistants encounter within those systems; and - The knowledge and skills physician assistants should exhibit when confronted with those diseases, disorders and assessments. Medical Content Categories % Allocation: Cardiovascular System 13% Dermatologic System 5% Endocrine System 7% Eyes, Ears, Nose, and Throat 7% Gastrointestinal System/Nutrition 9% Genitourinary... Show more

A 55-year-old male presents with headache, dizziness, weakness, fatigue, and blurred vision. Physical examination reveals systolic hypertension, engorged retinal veins, and splenomegaly. Bloodwork reveals hematocrit of 57%, elevated red cell mass, neutrophilic leukocytosis, increased basophils and eosinophils, and increased numbers of large, bizarre platelets. Based on the patient’s presentation, physical examination, and lab results, which of the following is the most appropriate diagnosis?






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