A 58-year-old man and his wife come to the clinic. He complains of skin flushing, dizziness, itching, nausea, and vomiting. He is tachycardic (120 bpm). His blood pressure is 150/102. An EKG shows regular heart rhythm with no missing QRS complexes. He has been prescribed niacin (vitamin B3) for hypercholesterolemia and hypertriglyceridemia. The patient is unsure of his dose, but he takes 4 tablets twice daily. The patient recently changed the type of over-the-counter niacin he was using from tablets to capsules, because the capsules are less expensive. His wife thinks the patient has been taking 1,000-mg tablets. This would make his current dose 8,000 mg daily, or 8 grams. Niacin capsules are available in 250–500 mg doses. If the patient was previously taking four 250-mg capsules twice daily, he was taking 2,000 mg, or 2 grams daily. If the capsules he previously took were 500 mg, he was taking 4,000 mg daily, or 4 grams. What do you suspect is this patient’s diagnosis?

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The material on the PANCE and PANRE is organized by the NCCPA into two dimensions, as indicated in the content blueprint for the examination. - Organ systems and the diseases, disorders and medical assessments physician assistants encounter within those systems; and - The knowledge and skills physician assistants should exhibit when confronted with those diseases, disorders and assessments. Medical Content Categories % Allocation: Cardiovascular System 13% Dermatologic System 5% Endocrine System 7% Eyes, Ears, Nose, and Throat 7% Gastrointestinal System/Nutrition 9% Genitourinary... Show more

A 58-year-old man and his wife come to the clinic. He complains of skin flushing, dizziness, itching, nausea, and vomiting. He is tachycardic (120 bpm). His blood pressure is 150/102. An EKG shows regular heart rhythm with no missing QRS complexes. He has been prescribed niacin (vitamin B3) for hypercholesterolemia and hypertriglyceridemia. The patient is unsure of his dose, but he takes 4 tablets twice daily. The patient recently changed the type of over-the-counter niacin he was using from tablets to capsules, because the capsules are less expensive. His wife thinks the patient has been taking 1,000-mg tablets. This would make his current dose 8,000 mg daily, or 8 grams. Niacin capsules are available in 250–500 mg doses. If the patient was previously taking four 250-mg capsules twice daily, he was taking 2,000 mg, or 2 grams daily. If the capsules he previously took were 500 mg, he was taking 4,000 mg daily, or 4 grams. What do you suspect is this patient’s diagnosis?






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