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Regulation of Transcription in Prokaryotes topics include: gene regulation, regulation levels, activators and repressors in positive and negative regulation, transcriptional regulation in eukaryotes, methylation of eukaryotic dna controls gene expression, x-chromosomes inactivation and rnas in gene regulation.
Transcription in prokaryotes is regulated by operons, which are regions of DNA that contain one or more genes that code for proteins. Operons also include a promoter and an operator, which is a region where regulatory proteins bind.
Transcription factors in prokaryotes sense changes in the environment and metabolic states. The transcription of an operon is controlled by the operator, which is next to the transcription initiation site. The i gene encodes a protein that regulates transcription by binding to the operator. Prokaryotes use simple activators and repressors to control transcription. For some genes, both may be used for regulation, while for others, only one is needed. There are three ways to control the transcription of an operon: Repressive control, Activator control, Inducible control. The activator is attached to the activator site, which is either directly in the promoter region or near the promoter region. The activator promotes the attachment of the RNA polymerase to the promoter. The repressor binds to the operator region, which is downstream from the promoter.
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