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Molecular Biology Practice Test: Regulation of Transcription in Prokaryotes
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Avg score: 61% Most missed: “Which of the following about the enhancers is false?”
Regulation of Transcription in Prokaryotes topics include: gene regulation, regulation levels, activators and repressors in positive and negative regulation, transcriptional regulation in eukaryotes, methylation of eukaryotic dna controls gene expression, x-chromosomes inactivation and rnas in gene regulation. Transcription in prokaryotes is regulated by operons, which are regions of DNA that contain one or more genes that code for proteins. Operons also include a promoter and an operator, which is a region where regulatory proteins bind.  Transcription factors in prokaryotes sense changes... Show more
Molecular Biology Practice Test: Regulation of Transcription in Prokaryotes
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25 Questions

1. What effect would a loss-of-function mutation have on the expression of the gene encoding the catabolite activator protein of the lac operon?
2. Which of the following is not present in the β-galactosidase structural gene and thus is not transcribed by the same promoter?
3. Presence of lactose itself induces the production of β-galactoside transferase.
4. In which stage of the cell cycle the Barr body can be identified?
5. Which of the following is true about tryptophan operon?
6. The investigation of the lac operon for the metabolism of lactose was done by __________
7. How many mechanisms are present to enhance transcription by the enhancer molecules?
8. Gene imprinting involves ___________
9. Which of the following is false about amino acid modification and activity?
10. The functional product of the Xist gene is ___________
11. Immunoglobulin enhancers are active in which of the following cell types?
12. In humans CpG islands are generally located in the ____________
13. De-novo methylation is done in the newly synthesized DNA strand at opposite positions of the methylated sites on the parent strand.
14. De-novo methylation leads to the phenomenon of genetic imprinting in the offspring.
15. Methylation of cytosine increases the transition mutation of cytosine to __________
16. The activation domain of activators recruits transcriptional factors to proper sites on the DNA.
17. If the lac operon of the genome of bacteria is always active it has a defect in which region of the operon?
18. Protein kinases transfer phosphate groups to the side chains of which of the following?
19. Which of the following is incorrect about the inactive state of the Ras protein?
20. Which of the following is false about bacterial tryptophan operon?
21. With respect to the methylation of bases which of the following is correct?
22. Which of the following about the enhancer sequence is incorrect?
23. In the case of lac operon, the gene expression is inhibited by __________
24. The Intergenic CpGs are more commonly methylated than in the intragenetic region.
25. How many enzymes are produced in the lac operon under the same promoter?