Pathophysiology Practice Test: Epigenetics and Disease — Flashcards | Pathophysiology 101 | FatSkills

Pathophysiology Practice Test: Epigenetics and Disease — Flashcards

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Epigenetics is the study of how changes to a gene's DNA can affect an individual without changing the DNA sequence. These changes can contribute to disease. 

Some possible causes of epigenetic changes include: Diet, Stressors, and Environmental pollutants. 

Epigenetic changes are responsible for human diseases, including:
Various cancers
Autoimmune disorders
Neurological disorders
Fragile X syndrome
Angelman's syndrome
Prader-Willi syndrome 

Epigenetic alterations cause chromatin remodeling and altered gene expression. This can lead to inflammation, proliferation, atrophy, and hypertrophy. 
Epigenetic therapy is a type of treatment that uses medicines to fix changes in DNA that might have caused cancer. This helps bring the DNA back to how it was before cancer started. 
However, there are potential risks associated with epigenetic interventions, including: adverse drug reactions, developmental abnormalities, and cancer. 

Related Test: Pathophysiology Practice Test: Genes and Genetic Diseases

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When considering abnormal epigenetic modifications, what factor is currently being viewed as strongly associated with the development of some cancers?
Environmental stressors
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