BIO301 Final Exam (Cell Biology)
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MCQs on the cell and its structures, including molecular compounds, structural features, and organelles including the nucleus, cytoskeleton, and extracellular matrix. Particular emphasis on transport mechanisms and membrane trafficking, cellular signaling, the cell cycle including mitosis and meiosis, and gene expression.
 

BIO301 Final Exam (Cell Biology)
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25 Questions

1. If you were an active organism (for example, an animal) and wanted to store energy efficiently, what type of molecule would be best suited for this purpose?
2. Identify the stage of meiosis I prophase during which the following occurs: the spindle forms and nuclear envelope breaks down.
3. Which of these does not provide suggestive evidence of rRNA's catalytic action in ribosomes?
4. Identify the stage of meiosis I prophase during which Recombination occurs.
5. A researcher discovers that some of the mice she studies show gene-expression problems; more research reveals that they are expressing both copies of imprinted genes of which only one copy (either the maternal or paternal) should be expressed.What regulatory process is most likely in error in these mice?
6. Rb is a protein that plays different roles during the cell cycle depending on its level of phosphorylation. In G0 phase, what would its state and its role be?
7. In the extracellular matrix of lung cells, you would expect to find:
8. Which of the following is an example of symport?
9. Which of the following is an example of a repressor of transcription?
10. The process of oocyte formation is different from that of sperm formation. At what point in gametogenesis does this difference first become apparent?
11. When metaphase chromosomes are stained with dye, they show a pattern of dark and light bands; each chromosome's band pattern is unique but consistent to that chromosome, and each gene within a chromosome is regularly located within the same band. Which of the following indicates what this tells us about chromosome organization?
12. In mammals, a DNA damage signal will lead a cell to arrest the cell cycle. In what way will it accomplish this?
13. Cardiac-muscle cells that must communicate with adjacent cells using electric impulses most likely have what kind of junctions between them?
14. Epithelial cells that must control the movement of ions and molecules between adjacent cells most likely have what kind of junctions between them?
15. Which of the following types of organelles would you expect to see in abundance in liver cells?
16. Which of the following is true of guanalyl cyclase receptors?
17. The following protein example describes which level of its structure? A glucose transporter is made up of many α helices.
18. What organelle would be used to degrade bacteria taken in by the cell via phagocytosis?
19. Identify the type of receptor based on its description: these receptors are monomeric, and their cytosolic domains do not have any catalytic properties.
20. Identify the mitotic phase or cell behavior during which the following occurs in animal cells: chromosomes are lined up along the mitotic spindle.
21. Which of the following is not one of the ways in which meiosis is different from mitosis?
22. A researcher observes that her patient does not have an appropriate physiological response to inflammation; his leukocytes do not appear to interact properly with endothelial cells at the sites of inflammation. The patient may have a problem with what cell-adhesion molecules?
23. During which phase of mitosis would you first be able to distinguish the difference between a cell undergoing closed vs. open mitosis?
24. Suppose the Gα subunit of a G-protein-coupled receptor could not hydrolyze GTP. Which of the following represents the most direct effect this would have on the G-protein-coupled-receptor process?
25. Which of these methods of membrane transport is always active (that is, always transports molecules against their concentration gradients)?

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