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UK Medicine Practice Questions

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1. Breast-cancer: How would you manage it?

2. Lung-cancer: What is the most common mutation in lung cancer?

Vomiting: hypokalaemia + metabolic alkalosis diarrhoea: hypokalaemia + metabolic acidosisMdt including a breast nurse surgery: wle or mastectomy (or neoadjuvant rx then wle) +/- breast reconstrution + slnb or ln clearance (gives npi = 0.2 * tumour size in cm + hist grade + nodal status. Also er/pr/her2 sensitivity) radiotherapy adjuvant rx: hormonal (tamoxifen, a.i, gnrh agonist), chemotherapy (fec, epirubicin can cause ccf and leukaemia so select pts), targeted e.g herceptin Infection (e.g hep b, strep viridans, malaria), sle, malignancy associated, sleP53 guardian of the genome""

3. Glomerulonephritis: What are the causes of membranous glomerulonephritis?

Infection (e.g hep b, strep viridans, malaria), sle, malignancy associated, sleVomiting: hypokalaemia + metabolic alkalosis diarrhoea: hypokalaemia + metabolic acidosisMdt including a breast nurse surgery: wle or mastectomy (or neoadjuvant rx then wle) +/- breast reconstrution + slnb or ln clearance (gives npi = 0.2 * tumour size in cm + hist grade + nodal status. Also er/pr/her2 sensitivity) radiotherapy adjuvant rx: hormonal (tamoxifen, a.i, gnrh agonist), chemotherapy (fec, epirubicin can cause ccf and leukaemia so select pts), targeted e.g herceptin P53 guardian of the genome""

4. Electrolyte-imbalance: How does vomiting differ from diarrhoea?

Vomiting: hypokalaemia + metabolic alkalosis diarrhoea: hypokalaemia + metabolic acidosisMdt including a breast nurse surgery: wle or mastectomy (or neoadjuvant rx then wle) +/- breast reconstrution + slnb or ln clearance (gives npi = 0.2 * tumour size in cm + hist grade + nodal status. Also er/pr/her2 sensitivity) radiotherapy adjuvant rx: hormonal (tamoxifen, a.i, gnrh agonist), chemotherapy (fec, epirubicin can cause ccf and leukaemia so select pts), targeted e.g herceptin P53 guardian of the genome""Infection (e.g hep b, strep viridans, malaria), sle, malignancy associated, sle

5. Medical-definitions: hemosiderosis

Describes the presence of stainable iron in tissuesInfection (e.g hep b, strep viridans, malaria), sle, malignancy associated, sleMdt including a breast nurse surgery: wle or mastectomy (or neoadjuvant rx then wle) +/- breast reconstrution + slnb or ln clearance (gives npi = 0.2 * tumour size in cm + hist grade + nodal status. Also er/pr/her2 sensitivity) radiotherapy adjuvant rx: hormonal (tamoxifen, a.i, gnrh agonist), chemotherapy (fec, epirubicin can cause ccf and leukaemia so select pts), targeted e.g herceptin P53 guardian of the genome""

6. Leukaemia: What is the typical presentation of aml?

7. Jaundice: why does urine which is left to stand in contact with the air turn orange-red in colour?

8. Churg-strauss: What is needed for diagnosis?

Infection (e.g hep b, strep viridans, malaria), sle, malignancy associated, sleMdt including a breast nurse surgery: wle or mastectomy (or neoadjuvant rx then wle) +/- breast reconstrution + slnb or ln clearance (gives npi = 0.2 * tumour size in cm + hist grade + nodal status. Also er/pr/her2 sensitivity) radiotherapy adjuvant rx: hormonal (tamoxifen, a.i, gnrh agonist), chemotherapy (fec, epirubicin can cause ccf and leukaemia so select pts), targeted e.g herceptin The american college of rheumatology (acr) has proposed 6 criteria for the diagnosis of churg-strauss syndrome. The presence of 4 or more criteria yields a sensitivity of 85% and a specificity of 99.7%. (1) asthma (wheezing, expiratory rhonchi) (2) eosinophilia of more than 10% in peripheral blood (3) paranasal sinusitis (4) pulmonary infiltrates (may be transient) (5) histological proof of vasculitis with extravascular eosinophils (6) mononeuritis multiplex or polyneuropathy.P53 guardian of the genome""

9. loop-diureticsimport:-duplicate: How do they work?

10. neurofibromatosis-type-1import:-duplicate: What is the differential?

Infection (e.g hep b, strep viridans, malaria), sle, malignancy associated, sleP53 guardian of the genome""Mccune-albright syndrome (2 of polyostic fibrous dysplasia, cafe-au-lait spots, and endocrine hyperfunction) multiple lentigines (lentigo = small, flat, pigmented, spot on skin) urticaria pigmentosaMdt including a breast nurse surgery: wle or mastectomy (or neoadjuvant rx then wle) +/- breast reconstrution + slnb or ln clearance (gives npi = 0.2 * tumour size in cm + hist grade + nodal status. Also er/pr/her2 sensitivity) radiotherapy adjuvant rx: hormonal (tamoxifen, a.i, gnrh agonist), chemotherapy (fec, epirubicin can cause ccf and leukaemia so select pts), targeted e.g herceptin

11. Cardiac-physiology: What is preload?

12. Depression: What is required for an icd-10 diagnosis?

2 typical symptoms + 2 core symptoms, must have symptoms for more than 2/52, must represent a change from normal for pt which can't be explained by medicines/drugs/psych problems e.g bereavement, must cause sig distress +/or impairment of social/occupational/general function.P53 guardian of the genome""Mdt including a breast nurse surgery: wle or mastectomy (or neoadjuvant rx then wle) +/- breast reconstrution + slnb or ln clearance (gives npi = 0.2 * tumour size in cm + hist grade + nodal status. Also er/pr/her2 sensitivity) radiotherapy adjuvant rx: hormonal (tamoxifen, a.i, gnrh agonist), chemotherapy (fec, epirubicin can cause ccf and leukaemia so select pts), targeted e.g herceptin Infection (e.g hep b, strep viridans, malaria), sle, malignancy associated, sle

13. Blood-transfusion: briefly describe delayed haemolytic and serological transfusion reactions.

P53 guardian of the genome""Infection (e.g hep b, strep viridans, malaria), sle, malignancy associated, slePre-transfusion patient has undetectably low antibodies to donor antigen. Transfusion. Reaction. Antibodies detectable 1-2 weeks later. No specific treatment is indicated.Mdt including a breast nurse surgery: wle or mastectomy (or neoadjuvant rx then wle) +/- breast reconstrution + slnb or ln clearance (gives npi = 0.2 * tumour size in cm + hist grade + nodal status. Also er/pr/her2 sensitivity) radiotherapy adjuvant rx: hormonal (tamoxifen, a.i, gnrh agonist), chemotherapy (fec, epirubicin can cause ccf and leukaemia so select pts), targeted e.g herceptin

14. Ankylosing-spondylitis: How is it diagnosed? What tests would you do?

Mdt including a breast nurse surgery: wle or mastectomy (or neoadjuvant rx then wle) +/- breast reconstrution + slnb or ln clearance (gives npi = 0.2 * tumour size in cm + hist grade + nodal status. Also er/pr/her2 sensitivity) radiotherapy adjuvant rx: hormonal (tamoxifen, a.i, gnrh agonist), chemotherapy (fec, epirubicin can cause ccf and leukaemia so select pts), targeted e.g herceptin Infection (e.g hep b, strep viridans, malaria), sle, malignancy associated, sleDiagnosis is clinical. Sacroilitis is the earliest feature (xr may be normal in early disease, mri is more sensitive): look for irregularities, erosions or sclerosis affecting the sacroiliac joints. Spine is affected with characteristic syndesmophytes (bony proliferations due to enthesitis between ligaments and the vertebrae - these fuse with the above vertebral body causing ankylosis). In the later stages calcification of ligaments with ankylosis lead to a 'banboo spine' appearance. Also: fbc (normochromic anaemia), increased esr, crp, hla-b27P53 guardian of the genome""

15. long-qt-syndrome-import:-duplicate: What is it?

Infection (e.g hep b, strep viridans, malaria), sle, malignancy associated, sleLong qt syndrome (lqts) is a congenital disorder characterized by a prolongation of the qt interval on ecg and a propensity to ventricular tachyarrhythmias, which may lead to syncope, cardiac arrest, or sudden death.P53 guardian of the genome""Mdt including a breast nurse surgery: wle or mastectomy (or neoadjuvant rx then wle) +/- breast reconstrution + slnb or ln clearance (gives npi = 0.2 * tumour size in cm + hist grade + nodal status. Also er/pr/her2 sensitivity) radiotherapy adjuvant rx: hormonal (tamoxifen, a.i, gnrh agonist), chemotherapy (fec, epirubicin can cause ccf and leukaemia so select pts), targeted e.g herceptin

16. Cxr: at What level should the horizontal fissure in the right lung run?

P53 guardian of the genome""From the hilum to the level of the 6th rib at the axillary line (collapse can distort this)Infection (e.g hep b, strep viridans, malaria), sle, malignancy associated, sleMdt including a breast nurse surgery: wle or mastectomy (or neoadjuvant rx then wle) +/- breast reconstrution + slnb or ln clearance (gives npi = 0.2 * tumour size in cm + hist grade + nodal status. Also er/pr/her2 sensitivity) radiotherapy adjuvant rx: hormonal (tamoxifen, a.i, gnrh agonist), chemotherapy (fec, epirubicin can cause ccf and leukaemia so select pts), targeted e.g herceptin

17. Amyloidosisimport:-duplicate duplicate:-front: What are the three main types?

Mdt including a breast nurse surgery: wle or mastectomy (or neoadjuvant rx then wle) +/- breast reconstrution + slnb or ln clearance (gives npi = 0.2 * tumour size in cm + hist grade + nodal status. Also er/pr/her2 sensitivity) radiotherapy adjuvant rx: hormonal (tamoxifen, a.i, gnrh agonist), chemotherapy (fec, epirubicin can cause ccf and leukaemia so select pts), targeted e.g herceptin P53 guardian of the genome""Infection (e.g hep b, strep viridans, malaria), sle, malignancy associated, sle1. Al amyloid (primary amyloidosis) clonal proliferation of a plasma cell that produces amyloid, deposition in kidneys, heart, nerves, gut, vasculature, causes disease. 2. Aa amyloid (secondary amyloidosis) amyloid derived from saa so any cause of chronic inflammation can cause this e.g ra, ibd, chronic infection etc. Deposition in kidneys, liver, and spleen causes disease. 3. Familial amyloidosis. Group of autosomal dominant disorders, usually causes sensory or autonomic neuropathy +/- cardiac involvment.

18. Gout: What may superficial tophi lead to?

P53 guardian of the genome""Ulceration of the overlying skinMdt including a breast nurse surgery: wle or mastectomy (or neoadjuvant rx then wle) +/- breast reconstrution + slnb or ln clearance (gives npi = 0.2 * tumour size in cm + hist grade + nodal status. Also er/pr/her2 sensitivity) radiotherapy adjuvant rx: hormonal (tamoxifen, a.i, gnrh agonist), chemotherapy (fec, epirubicin can cause ccf and leukaemia so select pts), targeted e.g herceptin Infection (e.g hep b, strep viridans, malaria), sle, malignancy associated, sle

19. Cancer: What type of hormone do malignant tumours most often secrete?

Peptide hormones e.g acth not steroid hormones e.g cortisolMdt including a breast nurse surgery: wle or mastectomy (or neoadjuvant rx then wle) +/- breast reconstrution + slnb or ln clearance (gives npi = 0.2 * tumour size in cm + hist grade + nodal status. Also er/pr/her2 sensitivity) radiotherapy adjuvant rx: hormonal (tamoxifen, a.i, gnrh agonist), chemotherapy (fec, epirubicin can cause ccf and leukaemia so select pts), targeted e.g herceptin P53 guardian of the genome""Infection (e.g hep b, strep viridans, malaria), sle, malignancy associated, sle

20. Differentials: haemoptysis

P53 guardian of the genome""Mdt including a breast nurse surgery: wle or mastectomy (or neoadjuvant rx then wle) +/- breast reconstrution + slnb or ln clearance (gives npi = 0.2 * tumour size in cm + hist grade + nodal status. Also er/pr/her2 sensitivity) radiotherapy adjuvant rx: hormonal (tamoxifen, a.i, gnrh agonist), chemotherapy (fec, epirubicin can cause ccf and leukaemia so select pts), targeted e.g herceptin 1. Respiratory causes: infective - acute bronchitis, pneumonia, lung abscess, bronchiectasis, tb, fungi, paragonimiasis (parasitic disease causing subacute chronic inflammation of the lung) neoplastic - primary or secondary vascular - lung infarction, vasculitis (wegener's, ra, sle, osler-weber-rendu), av fitulae, malformations parenchymal - diffuse interstitial fibrosis, sarcoidosis, haemosiderosis, goodpasture's syndrome, cystic fibrosis traumatic - wounds, post-intubation, foreign body 2. Cardiovascular causes (pulmonary hypertension): l-r shunt, left sided heart disease 3. Bleeding diathesesInfection (e.g hep b, strep viridans, malaria), sle, malignancy associated, sle

21. Corneal-ulcer: What antibiotics would you use?

P53 guardian of the genome""Infection (e.g hep b, strep viridans, malaria), sle, malignancy associated, sleExocin, ciprofloxacin hourly. Cefurozime and gentamycinMdt including a breast nurse surgery: wle or mastectomy (or neoadjuvant rx then wle) +/- breast reconstrution + slnb or ln clearance (gives npi = 0.2 * tumour size in cm + hist grade + nodal status. Also er/pr/her2 sensitivity) radiotherapy adjuvant rx: hormonal (tamoxifen, a.i, gnrh agonist), chemotherapy (fec, epirubicin can cause ccf and leukaemia so select pts), targeted e.g herceptin

22. Sirs: What is sepsis?

P53 guardian of the genome""Sirs occuring in the presence of infectionMdt including a breast nurse surgery: wle or mastectomy (or neoadjuvant rx then wle) +/- breast reconstrution + slnb or ln clearance (gives npi = 0.2 * tumour size in cm + hist grade + nodal status. Also er/pr/her2 sensitivity) radiotherapy adjuvant rx: hormonal (tamoxifen, a.i, gnrh agonist), chemotherapy (fec, epirubicin can cause ccf and leukaemia so select pts), targeted e.g herceptin Infection (e.g hep b, strep viridans, malaria), sle, malignancy associated, sle

23. Post-operative-complications: What is your standard description of these?

Mdt including a breast nurse surgery: wle or mastectomy (or neoadjuvant rx then wle) +/- breast reconstrution + slnb or ln clearance (gives npi = 0.2 * tumour size in cm + hist grade + nodal status. Also er/pr/her2 sensitivity) radiotherapy adjuvant rx: hormonal (tamoxifen, a.i, gnrh agonist), chemotherapy (fec, epirubicin can cause ccf and leukaemia so select pts), targeted e.g herceptin P53 guardian of the genome""Post-operative complications may be general or specific. General complications may be early (less than 24h), intermediate (2nd day to 2nd week) or late. Early complications include, atelectasis, respiratory distress and reactionary haemorrhage. Intermediate complications included atelectasis, pneumonia, p.e, urinary retention, uti, dvt, wound infection and dehiscence. Late complications include wound dehisence, incisional hernial, recurrent condition. Specific complications depend on the operation performed.Infection (e.g hep b, strep viridans, malaria), sle, malignancy associated, sle

24. Red-blood-cell-abnormalities-match-with-cause: macrocytic

B12 & folate deficiency, drugs e.g phenytoin, cytotoxics, alcohol, liver disease, rarely hypothyroidismP53 guardian of the genome""Infection (e.g hep b, strep viridans, malaria), sle, malignancy associated, sleMdt including a breast nurse surgery: wle or mastectomy (or neoadjuvant rx then wle) +/- breast reconstrution + slnb or ln clearance (gives npi = 0.2 * tumour size in cm + hist grade + nodal status. Also er/pr/her2 sensitivity) radiotherapy adjuvant rx: hormonal (tamoxifen, a.i, gnrh agonist), chemotherapy (fec, epirubicin can cause ccf and leukaemia so select pts), targeted e.g herceptin

25. Cycoplegiaimport:-duplicate duplicate:-front: What is it?

Paralysis of accomodation rendering the eye unable to focus on near objects.Mdt including a breast nurse surgery: wle or mastectomy (or neoadjuvant rx then wle) +/- breast reconstrution + slnb or ln clearance (gives npi = 0.2 * tumour size in cm + hist grade + nodal status. Also er/pr/her2 sensitivity) radiotherapy adjuvant rx: hormonal (tamoxifen, a.i, gnrh agonist), chemotherapy (fec, epirubicin can cause ccf and leukaemia so select pts), targeted e.g herceptin Infection (e.g hep b, strep viridans, malaria), sle, malignancy associated, sleP53 guardian of the genome""

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❤ If you liked Fatskills, consider supporting us by checking out The Life Manuals You Never Got.

About | Explore | User Guide | Topics | Subjects | Doubt Solver | Career Aptitude Test | Answers | Free Tools | What Should We Know? Privacy | Terms |

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All trademarks, logos and brand names are the property of their respective owners. All company, product and service names used in this website are for identification purposes only. Use of these names, trademarks and brands does not imply endorsement.

About | Explore | User Guide | Topics | Subjects | Doubt Solver | Career Aptitude Test | Answers | Free Tools | What Should We Know?
Privacy | Terms |

Without work one finishes nothing. - Ralph Waldo Emerson
© 2026 Fatskills.com