1. Bleomycin is used in most effective drug combination regiment for the chemotherapy of testicular carcinoma. Which one of the following statements about the drug is accurate?

2. A 19-year-old woman with recurrent sinusitis has been treated with different antibiotics on several occasions. During the course of one such treatment she developed a severe diarrhea and was hospitalized. Sigmoidoscopy revealed colitis, and pseudomembranes, were confirmed histologically. Which of the following drugs, administered orally, is most likely to be effective in the treatment of colitis due to C difficile?

3. Tetracycline is stored in the body in

4. Which fluoroquinolone has markedly enhanced activity against gram positive bacteria and anaerobes ?

5. Cephalosporins

6. Clarithromycin is used for the following

7. Clarithromycin and erythromycin have very similar spectrums of antimicrobial activity. The major advantage of clarithromytcin is that it

8. Adverse effects of ciprofloxacin are referable primarily to the following except

9. Which of the following antibiotics possess neuromuscular blocking action

10. Select the antibiotic with a high therapeutic index

11. If a patient gives history of urticaria, itching and swelling of lips following injection of penicillin G, then

12. Benzylpenicillin is not used orally because

13. Which aminoglycoside antibiotic causes more hearing loss than vestibular disturabance as toxic effect ?

14. The most frequent side effect of oral ampicillin is

15. Select the antibiotic whose dose must be reduced in patients with renal insufficiency

16. Cyclosporine

17. Amoxicillin + Clavulanic acid is active against the following organism except

18. Chloramphenicol is more active than tetracyclines against

19. The most important mechanism by which tetracycline antibiotics exert antiimicrobial action is

20. Which of the following statements about vancomycin is accurate?

21. Of the following which is the most important mechanism of concurrent acquisition of multidrug resistance among bacteria ?

22. Which of the following agents is not a broad spectrum antibiotic

23. Drug which interfere with the bacterial cell wall synthesis is

24. Penicillins are not effective against

25. ‘Red man syndrome’ has been associated with rapid intravenous injection of the following antibiotic