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Cell Biology Practice Test: Cell Signaling & Signal Transduction
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Avg score: 68% Most missed: “Inactivation of which of the following leads to detachment of the apoptotic cell…”
Topics include: Cell Signaling Systems, G-protein Receptors, Protein Phosphorylation, Calcium Role, Pathways Crosstalk, NO Role, & Apoptosis. Cell signaling, also known as signal transduction, is the transmission of molecular signals from the outside of a cell to its interior. This process is initiated by cell-surface receptors.  Signaling can control cell growth, movement, and metabolism. A signal transduction cascade is a series of chemical reactions that occurs inside the cell after a stimulus starts it.  Signal transduction pathways amplify the entering signal through signaling cascade... Show more
Cell Biology Practice Test: Cell Signaling & Signal Transduction
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25 Questions

1. How many types of calcium ion channels are present on ER membrane?
2. Which ions activate cyclin-dependent kinases, following fertilization?
3. Retinitis pigmentosa is an inherited disorder caused due to mutation in the gene that encodes for __________________
4. On the cytoplasmic site of GCPRs, the G-proteins bind to ___________________
5. Acetylcholine has the function of ________________________
6. Diabetes Mellitus is caused by defects in insulin signaling.
7. Which of the following synthesis is decreased (or stopped) when the blood glucose levels are high?
8. Protein kinases and phosphatases act by altering ______________ of the signaling proteins.
9. The development of Viagra is related to the discovery of nitric oxide as a ____________________
10. Which of the following is also termed as a death receptor?
11. Abnormal elevation of cytosolic Calcium can occur following a _____________
12. G-protein coupled receptors are referred to as seven-transmembrane receptors.
13. How many types of protein-tyrosine kinases are there?
14. Inactivation of which of the following leads to shrinkage of the nucleus?
15. Endocrine messengers are also called ___________________
16. Viagra is specific for which isoform of cGMP phosphodiesterase?
17. Adenoma is caused by the over-secretion of ____________________
18. The process by which extracellular messages translate into intracellular changes is termed _________________
19. The Cholera toxin produced by Vibrio cholera exerts its effect by _____________________
20. Cytokines serve as _____________________ for apoptosis.
21. To which of the following residues of the protein, the protein kinases do not add phosphate groups?
22. When the levels of glucose drop, alpha-cells in the pancreas secrete ____________________
23. Which of the following compounds is metabolized into nitric oxide?
24. The cytoplasmic protein-tyrosine kinases are activated indirectly by the extracellular signals.
25. The last proteins to involve in the apoptotic pathway induced by TNF are ______________________