Biopharmaceutics
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Biopharmaceutics
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25 Questions

1. A tablet of aceclofenac is given to a patient. The dose of aceclofenac was 200 mg, after 2 h the concentration was found to be 10 μg/ml. What is the volume of distribution of aceclofenac?
2. On a product, the label states 'protect from light'. What type of decomposition does the product undergoes?
3. The initial distribution of a drug into tissue is determined chiefly by
4. When the release of drug from a dosage form satisfies Higuchi's equation, the release of drug can be considered as
5. Which of the following barrier is responsible for transfer of nutrients from mother to foetus?
6. During the primary drying stage in lyophilization the temperature of the product must remain below its critical temperature. This temperature is termed
7. The rate of desorption is proportional to the
8. The term bioavailability refers to the
9. Which one of the following marker is used to measure total body water
10. Which one of the following is primarily not a chemical decomposition?
11. Which of the following junctions is responsible for low distribution of drug to cerebrospinal from blood
12. Calculate the dialysis clearance if the blood flow rate to the dialysis is 50 ml/min and concentration of drug entering and leaving the dialyzer dialyser is 100 and 20 μg/ml, respectively,
13. Compartment modelling is explained by assuming
14. Which of the following mechanisms of drug absorption is saturable type?
15. Which of the following process is responsible for loss of drug irreversible
16. Glucoronidation process results in
17. According to the pH partition hypothesis the absorption of drug is maximum when
18. Innulin is used as a marker for measurement of
19. Sigma'Minus method is used to determine the ________
20. The applicability of Noyes-Whitney equation is to describe the
21. Which of the following binding site is not available in HSA?
22. Following is not true for pKa of a drug
23. Which statement is correct?
24. The half-life for first-order photolysis of cefotaxime solution containing 150 mg drug is 50 min. If 1ml aliquot after 90 min of exposure to light was found to contain 0.43 mg of cefotaxime, what was the original volume the solution?
25. Active tubular secretion is determined by

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