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UPSC Drug Inspector Examination Paper 2011
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UPSC Drug Inspector Examination Paper 2011
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25 Questions

1. Rosiglitazone 1. Should be used with caution in patients with cardiovascular disease. 2. Should not be used with glicazide. 3. Is a biguanide. Which of the above statement is/are correct?
2. As per the schedule 'Y' of the Drugs and Cosmetics Act, the animal toxicity study requirement for marketing of a drug depends upon tentative route and duration of administration in humans. In this context, which one of the following statements is incorrect?
3. Probenecid increases serum levels and prolongs activity of penicillin derivatives by
4. Which of the following is/are the symptoms of venous thrombosis? 1. Oedema 2. Lower leg becoming bluish in colour 3. Dry skin Select the correct answer using the code given below:
5. Following adverse effects are rightly paired with a causative anti-malarial drug except:
6. In one of the clinical trails of vaccine, there were 6 deaths reported by the media. You have been deputed by authority to investigate the causality of incidence. Inspection of the following documents will be helpful except:
7. The president of India has no power to grant pardon under Article 72 of the Constitution of India where sentence
8. The local anesthetics exert their action by blocking of the following types of ion channels:
9. 0.9% w/v sodium chloride has a freezing point depression of
10. Which one among the following statements is not correct?
11. The Chairman of the Investigational New Drug (INd) committee in India is
12. Following antibiotics have been correctly paired to their mechanism of action, except:
13. Assume that for a digoxin, the therapeutic range is cited as Cavg 5.5 = 0.8 '2mg/ml. If the patient is assumed to have an estimated digoxin t1/2 of 48 hours, how long would you wait to take serum digoxin concentration measurement and when during the dosing interval would you schedule it?
14. Which one among the following is observed in first order kinetic?
15. Which among the following is/are units of RAM? 1. Giga byte and Mega byte 2. RPM 3. GBPS and MBPS Select the correct answer the using the code given below:
16. Good Laboratory Practice (GLP) certification is issued in India by
17. Prostaglandins have effect on a variety of tissues in human body. The different Prostaglandins may have different effects. Which one of the following statement is not correct?
18. Which one of the following acids has the highest degree of ionization in an aqueous solution?
19. An alcoholic solution contains 57.77% u/v alcohol. The strength will be labelled as
20. Anti-inflammatory action of glucocorticoids is due to blocking of
21. Which equation is used to predict the stability of a drug product at room temperature from experiment at accelerated temperature?
22. The pharmacokinetics 'half-life' of which one of the following resembles to its pharmacodynamic 'half-life'?
23. Dose dumping is a problem in the formulation of
24. Which one of the following is second generation H1-Anti histamine?
25. A new drug has completed phase-I clinical trial in USA, the pharmaceutical company wants to do the multicentric, multinational trial including in India. The firm will apply in India to conduct

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