By Fatskills Exam Guides Team — the exam nerds behind 28,500+ quizzes and 2.1M practice questions across 500+ global exams.
Intermediate – requires precise differentiation of structures, components, and exceptions commonly tested in first-year biology exams.
Question: Which of the following is a feature shared by both prokaryotic and eukaryotic cells? A) Membrane-bound nucleus B) 80S ribosomes C) Phospholipid bilayer plasma membrane D) Mitochondria Answer: C Explanation: Both cell types have a phospholipid bilayer as the plasma membrane. Why the top distractor is wrong: D (mitochondria) are only found in eukaryotic cells.
Question: A cell is observed to contain peptidoglycan in its cell wall and lacks a nucleus. It most likely belongs to which domain? A) Eukarya B) Archaea C) Bacteria D) Protista Answer: C Explanation: Peptidoglycan is a defining feature of bacterial cell walls. Why the top distractor is wrong: B (Archaea) lack peptidoglycan, though they may have similar structural polymers.
Question: Which structure is present in plant cells but absent in animal cells? A) Lysosome B) Mitochondrion C) Chloroplast D) Golgi apparatus Answer: C Explanation: Chloroplasts are organelles for photosynthesis and are found only in plants and algae. Why the top distractor is wrong: A (lysosomes) are common in animal cells and occasionally found in plant vacuoles, but not a defining feature.
Question: Mitochondria are thought to have evolved from free-living prokaryotes due to all of the following EXCEPT: A) They contain circular DNA B) They have 80S ribosomes C) They reproduce by binary fission D) They have double membranes Answer: B Explanation: Mitochondria have 70S ribosomes, not 80S, supporting prokaryotic origin. Why the top distractor is wrong: A is correct evidence—circular DNA is typical of prokaryotes.
Question: Which of the following cells lacks a nucleus? A) Yeast cell B) Human neuron C) Escherichia coli D) Onion root cell Answer: C Explanation: E. coli is a prokaryote and lacks a membrane-bound nucleus. Why the top distractor is wrong: A (yeast) is a eukaryotic fungus and has a nucleus.
Question: The nucleolus is best described as the site of: A) DNA replication B) ATP synthesis C) Ribosomal RNA synthesis D) Protein degradation Answer: C Explanation: The nucleolus synthesizes rRNA and assembles ribosomal subunits. Why the top distractor is wrong: A (DNA replication) occurs throughout the nucleus, not specifically in the nucleolus.
Question: Which organelle modifies and packages proteins for secretion? A) Rough endoplasmic reticulum B) Smooth endoplasmic reticulum C) Golgi apparatus D) Lysosome Answer: C Explanation: The Golgi apparatus modifies, sorts, and packages proteins into vesicles for export. Why the top distractor is wrong: A synthesizes proteins but does not package them for secretion.
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