By Fatskills Exam Guides Team — the exam nerds behind 28,500+ quizzes and 2.1M practice questions across 500+ global exams.
Intermediate – requires distinguishing structural and functional differences across domains and organelles, with attention to exceptions and evolutionary evidence.
Trap: All cells with cell walls have peptidoglycan – Fact: Only bacteria have peptidoglycan; archaea, plants (cellulose), and fungi (chitin) have different wall compositions. Trap: Ribosome size is the same across all cells – Fact: Prokaryotes use 70S ribosomes; eukaryotes use 80S in cytoplasm, but mitochondria and chloroplasts retain 70S. Trap: The nucleus is the only organelle with a double membrane – Fact: Mitochondria and chloroplasts also have double membranes. Trap: Eukaryotes are always larger and more complex than prokaryotes – Fact: While generally true, some bacteria (e.g., Thiomargarita namibiensis) can be larger than typical eukaryotic cells. Trap: All eukaryotic cells have a cell wall – Fact: Only plants, fungi, and some protists have cell walls; animal cells do not.
Question: Which of the following is a defining feature of prokaryotic cells? A) Membrane-bound nucleus B) 80S ribosomes in the cytoplasm C) Presence of peptidoglycan in the cell wall D) Endoplasmic reticulum Answer: C Explanation: Peptidoglycan is a component of bacterial cell walls, a hallmark of prokaryotes. Why the top distractor is wrong: A is incorrect because prokaryotes lack a membrane-bound nucleus.
Question: Where are 70S ribosomes found in eukaryotic cells? A) Cytoplasm B) Nucleus C) Mitochondria D) Golgi apparatus Answer: C Explanation: Mitochondria contain 70S ribosomes, similar to prokaryotes, supporting endosymbiotic theory. Why the top distractor is wrong: A is incorrect because cytoplasmic ribosomes in eukaryotes are 80S.
Question: Which structure is present in plant cells but not in animal cells? A) Lysosome B) Central vacuole C) Peroxisome D) Smooth ER Answer: B Explanation: The large central vacuole is a key feature of mature plant cells, maintaining turgor pressure. Why the top distractor is wrong: A is incorrect because lysosomes are primarily found in animal cells.
Question: Which of the following provides evidence for the endosymbiotic theory? A) Mitochondria have linear DNA B) Chloroplasts are surrounded by a single membrane C) Mitochondria replicate by binary fission D) Lysosomes contain hydrolytic enzymes Answer: C Explanation: Mitochondria divide independently via binary fission, similar to bacteria. Why the top distractor is wrong: A is incorrect because mitochondria have circular, not linear, DNA.
Question: Which cell type lacks a nucleus but contains ribosomes? A) Human red blood cell B) Escherichia coli C) Mature plant sieve tube element D) Fungal hypha Answer: B Explanation: E. coli is a prokaryote with ribosomes but no nucleus. Why the top distractor is wrong: A is incorrect because mature red blood cells lack both nucleus and ribosomes.
Question: What is the primary component of fungal cell walls? A) Peptidoglycan B) Cellulose C) Chitin D) Silica Answer: C Explanation: Fungi have cell walls composed of chitin, a nitrogen-containing polysaccharide. Why the top distractor is wrong: A is incorrect because peptidoglycan is found in bacteria, not fungi.
Question: Which organelle is responsible for lipid synthesis and detoxification in liver cells? A) Rough ER B) Golgi apparatus C) Lysosome D) Smooth ER Answer: D Explanation: Smooth ER synthesizes lipids and detoxifies drugs, especially in hepatocytes. Why the top distractor is wrong: A is incorrect because rough ER synthesizes proteins, not lipids.
Join 4M+ learners. Unlock unlimited quizzes, wrong-answer tracking, flashcards + reminders, study guides, and 1-on-1 challenges.