1. Which mode of inheritance results in both allele being detected equally in the heterozygous phenotype?

2. Which of these statements about heritability is FALSE? - - a. Twin studies can offer insight into broad sense heritability of human traits - b. Broad sense heritability measures the ratio of genetic variation to phenotypic variance - c. Narrow-sense heritability measures the contribution of additive genotypic variance to phenotypic variance - d. Heritability measures the extent to which environmental variation contributes to the total phenotypic variation - e. High narrow sense heritability values are correlated with a great degree of response to artificial selection

3. Shotgun sequencing requires all of the following except?

4. The enzyme B-galactosidase catalyzes what reaction?

5. In the Hershey-Chase experiment, bacteriophages were produced in either 32P-containing or 35S-containing medium. Where were these isotopes eventually detected when the radioactively-labeled bacteriophages were introduced with the bacterial cells?

6. King George III of England and other members of the Royal Family were afflicted with a series of strance, seemingly unrelated symptoms including abdominal pain, rapid pulse, convulsions, and insanity. It has been determined that he likely suffered from porphyria, caused by a mutation in a single allele. What is the genetic term describing the alteration of multiple, distinct traits of an organism by a mutation in a single gene?

7. Which region of the lac operon would you target if you wanted to disrupt the -10 and -35 consensus sequences?

8. Most of the regulation of gene expression in bacteria occurs at the ______ level.

9. A researcher is annotating a newly-sequenced chromosome that they constructed from contigs sequenced from a sample of Antarctic ice. The cell/organism that the chromosome came from is not known, however it yielded a single circular chromosome. You are asked to run a BLAST search to help this researcher identify the most related organism in GenBank. What would be the best strategy?

10. During which phase of the cell cycle does the cell initiate replication of its nuclear DNA?

11. Cloning animals by nuclear implantation involves all of the following except? - - a. Induction of cell division and implantation of blastocyst in the surrogate mother - b. Removal of somatic cells and extraction of a diploid donor nucleus from the animal to be cloned - c. Removal of an egg, extraction of the nucleus, and injection of the diploid donor nucleus - d. A low frequency of success likely due to variations in the completeness of epigenetic programming of the somatic cell nucleus - e. Fertilization of the cell egg with a sperm cell followed by implantation in a surrogate mother

12. Trans-acting regulators of gene expression include:

13. A mutant DNA polymerase that increases the frequency of strand slippage would increase the frequency of which type of mutation?

14. sexual reproduction uses ______ to generate ______ gametes, which joins at fertilization.

15. Deafness is caused by recessive mutations in any one of at least five genes. Two deaf individuals have nine children, all of whom have normal hearing. Which of the following can you conclude?

16. Which of the following mutants are noninducible? - - a. ​lacIs - b. lacI+ - c. lacI- - d. lacOc - e. lacO+

17. The most common cause of cancer formation is ______.

18. Which type of sequencing involves first creating a physical map?

19. A polycistronic mRNA contains multiple ______.

20. What is the process by which a bacterium switches from the lysogenic cycle to the lytic cycle?

21. Age is the greatest of all risk factors for cancer because ______.

22. sickle cell anemia is:

23. Groups of genes that are evolutionary related are called ______.

24. The incidence of Tay Sachs disease, an autosomal recessive disorder, is approximately 1 in 3,5000 in a certain population of Ashkenazi Jews. Assuming H-W equilibrium, what is the frequency of carries for the Tay Sachs allele in this population?

25. localized mutations that occur at a specific location rather than over a large span on a gene are better known as what?