GPAT Paper 2010
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GPAT Paper 2010
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25 Questions

1. Drugs in suspensions and semi-solid formulations always degrade by
2. Which of the following non-opioid analgesics is a prodrug?
3. X-ray crystallographic analysis of an optically active compound determines its
4. Choose the right combination:
5. Improvement of memory in Alzheimer's disease is brought about by drugs which increase transmission in
6. The ability of human eye using illuminated area to detect a particle is limited to
7. Indicate the HPLC detector that is most sensitive to change in temperature:
8. A metabolite obtained from Aspergillus terreus that can bind very tightly to HMG CoA reductase enzyme is
9. Alkaloids are not precipitated by
10. Amitryptyline is synthesized from the following starting material:
11. For glyburide, all of the following metabolic reactions are logical except:
12. The given antibiotic is an example of ansamycins:
13. Which one of the following is used as a mood stabilizer for bipolar disorder and also in certain epileptic convulsions?
14. An isosteric replacement for carboxylic acid group is
15. Which filler can not be used for the preparation of tablets for amine containing basic drugs to avoid discolouration of the tablets?
16. Proton pump inhibitors like omeprazole and lansoprazole contain the following ring system:
17. The common structural feature amongst the three categories of anti-convulsant drugs barbiturates, succinimides and hydantoins is
18. The amount of barbaloin present in Aloe vera is
19. In thiazides, following substituent is essential for diuretic activity:
20. Drugs following one compartment open model pharmacokinetics eliminate
21. Which one of the following statements is wrong?
22. Cardiac glycosides have the following configuration in the Aglycone part of the steroid nucleus:
23. Streptomycin cannot be given orally for treatment of tuberculosis because
24. Glass transition temperature is detected through
25. Which one of the following drugs specifically inhibits calcineurin in the activated T lymphocytes?

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