Hepatitis: is the risk of cancer greater in auto-immune or virus associated hepatitis?

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1. Hepatitis: is the risk of cancer greater in auto-immune or virus associated hepatitis?

Lancet sept 2003 rct found that la had several advantages including shorter duration of inpatient stay, less postoperative pain and fewer micturition difficulties (urinary retention).
Virus-associated
Prevelance: 0.2% female:male 9:1 more common in young 20-40, afro-carribean and asians rfs: hla b8, dr2, dr3 10% of relatives may be affected.
So called because looks normal on light microscopy. It is the commonest cause nephrotic syndrome in children (76% of nephrotic children, 20% of nephrotic adults). It is associated with hodgkin's disease. Atopy is a known aetiological factor. The presumed mechanism is that circulating t-cell factor causes damage to podocytes. Treatment is with corticosteroids and induces remission in 95% of children and 70% of adults. Cyclophosphamide and cyclosporin are used if frequent relapses or steroid side effects. Prognosis: approximatly 1% develop esrf

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Hepatitis: is the risk of cancer greater in auto-immune or virus associated hepatitis?

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