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A 2 year old boy is admitted to hospital after a right sided abdo mass extending across midline is found on routine examinatino. Patient is asymptomatic but unergoes surgical resection of mass. Microscopic exam of lesion shows sheets of small cells with hyperchromatic nuclei. Tumor cells encircle pink neurofibrillary structures. 1. What is diagnosis? 2. What is the associated aoncogene? 3. Abdo mass with hypertension and hematuria would suggest what instead? 4. What is mutation associated with that?

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The General Principles section of the USMLE covers these topics:
Biochemistry
Genetics
Microbiology
Pathology
Pharmacology


1. A 2 year old boy is admitted to hospital after a right sided abdo mass extending across midline is found on routine examinatino. Patient is asymptomatic but unergoes surgical resection of mass. Microscopic exam of lesion shows sheets of small cells with hyperchromatic nuclei. Tumor cells encircle pink neurofibrillary structures. 1. What is diagnosis? 2. What is the associated aoncogene? 3. Abdo mass with hypertension and hematuria would suggest what instead? 4. What is mutation associated with that?





 
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