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A 4 year old boy is brought to GP due to sore throat, cough and nasal congestion. Mother says that he has suffered from recurrent bacterial infections since he was 6 montsh old. Lab and genetic studies show patient has na inherited defect in one of the genes encode component of NADPH oxidase. 1. What is your diagnosis? 2. A defect in what is responsible for deficient leukocyte defense against microbes in this patient?

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The General Principles section of the USMLE covers these topics:
Biochemistry
Genetics
Microbiology
Pathology
Pharmacology


1. A 4 year old boy is brought to GP due to sore throat, cough and nasal congestion. Mother says that he has suffered from recurrent bacterial infections since he was 6 montsh old. Lab and genetic studies show patient has na inherited defect in one of the genes encode component of NADPH oxidase. 1. What is your diagnosis? 2. A defect in what is responsible for deficient leukocyte defense against microbes in this patient?





 
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