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A 54 year old man with a history of T2DM comes to doctor because of unresolved skin lesion on his foot. Lesion appeared several weeks ago but has expanded and become painful. Physical examination shows a 5 cm lesion with a black, necrotic center and raised erythematous edges. Gram stain of wound shows gram negative bacilli. 1. What is your diagnosis and why? 2. What other toxin mechanism of another infective organism has a similar action as this organisms toxin moa?

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The General Principles section of the USMLE covers these topics:
Biochemistry
Genetics
Microbiology
Pathology
Pharmacology


1. A 54 year old man with a history of T2DM comes to doctor because of unresolved skin lesion on his foot. Lesion appeared several weeks ago but has expanded and become painful. Physical examination shows a 5 cm lesion with a black, necrotic center and raised erythematous edges. Gram stain of wound shows gram negative bacilli. 1. What is your diagnosis and why? 2. What other toxin mechanism of another infective organism has a similar action as this organisms toxin moa?





 
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