40 year old man comes to ED he has: -Progressive memory loss -Confusion -Incontinence -CD4 Cell count of 25 He subsequently dies of desseminated aspergillosis. Microscopic exam of brain shows multifocal lymphohistiocytic infiltrates with numerous microglial nodules and scattered multinucleated giant cells. 1. What condition is most likely responsible for this patients neurologic symptoms and histologic findings? 2. What are the distinguishing features that suggest HIV encephalopathy?

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Neurology is the branch of medicine that focuses on the study, diagnosis, and management of conditions affecting the nervous system.


1. 40 year old man comes to ED he has: -Progressive memory loss -Confusion -Incontinence -CD4 Cell count of 25 He subsequently dies of desseminated aspergillosis. Microscopic exam of brain shows multifocal lymphohistiocytic infiltrates with numerous microglial nodules and scattered multinucleated giant cells. 1. What condition is most likely responsible for this patients neurologic symptoms and histologic findings? 2. What are the distinguishing features that suggest HIV encephalopathy?