43 year old man with lesion on penis for 1 year without response to topical treatment with bacitracin and hydrocortisone. Physical exam shows 1 cm opaque gray white flat penile plaque on shaft. Biopsy shows dysplastic squamous cells with increased nucleus to cytoplasmic ratio, crowding and lack of architectural organization involving full thickness of epithelium. Basement membrane is intact. 1. What is this condition?

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The development of the reproductive system begins with the formation of undifferentiated gonads and the paired mesonephric and paramesonephric ducts.


1. 43 year old man with lesion on penis for 1 year without response to topical treatment with bacitracin and hydrocortisone. Physical exam shows 1 cm opaque gray white flat penile plaque on shaft. Biopsy shows dysplastic squamous cells with increased nucleus to cytoplasmic ratio, crowding and lack of architectural organization involving full thickness of epithelium. Basement membrane is intact. 1. What is this condition?