A 42 yo comes to doctor has 1 week hx of fever, night sweats and rash on arms/legs. Past medical history significant for HIV/AIDS. Last CD4 count two months ago was 150. VItals are normal. Physical exam shows several clustered, violeceous nodules on arms/legs. Biopsy of one lesion shows a neutrophilic infiltrate and granulomatous changes. 1. What is occuring in this man? 2. What is the responsible organism?

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Connective tissue is the most abundant type of tissue in the body. It serves to connect and support other tissues and also has regulatory and immunologic functions. Connective tissue consists of cells, mainly fibroblasts, and an extracellular matrix (ECM).


1. A 42 yo comes to doctor has 1 week hx of fever, night sweats and rash on arms/legs. Past medical history significant for HIV/AIDS. Last CD4 count two months ago was 150. VItals are normal. Physical exam shows several clustered, violeceous nodules on arms/legs. Biopsy of one lesion shows a neutrophilic infiltrate and granulomatous changes. 1. What is occuring in this man? 2. What is the responsible organism?