A 55 year old man comes to GP for evaluation of skin lesions. Tells the GP that lesions have been spreading for last few months. The patient has normal vital signs. GP explains to the patient that he has an autoimmune reaction to the epidermal structure that connects cells together. Patient is treated with systemic corticosteroids. 1. What is the diagnosis? 2. What causes it? 3. How would you describe the skin lesions caused by this condition?

Connective tissue is the most abundant type of tissue in the body. It serves to connect and support other tissues and also has regulatory and immunologic functions. Connective tissue consists of cells, mainly fibroblasts, and an extracellular matrix (ECM).