Fatskills
Practice. Master. Repeat.
Study Guide: Paediatric Respiratory Conditions: Croup, Epiglottitis, RSV Bronchiolitis, Asthma
Source: https://www.fatskills.com/nursing-entrance-exams/chapter/paediatric-respiratory-conditions-croup-epiglottitis-rsv-bronchiolitis-asthma

Paediatric Respiratory Conditions: Croup, Epiglottitis, RSV Bronchiolitis, Asthma

By Fatskills Exam Guides Team — the exam nerds behind 28,500+ quizzes and 2.1M practice questions across 500+ global exams.

⏱️ ~7 min read

Paediatric Respiratory Conditions: Croup, Epiglottitis, RSV Bronchiolitis, Asthma

A high-density, practical guide for clinicians, nurses, and students


What Is This?

This guide covers four critical paediatric respiratory conditions: croup, epiglottitis, RSV bronchiolitis, and asthma. You’ll learn to recognise, assess, and manage these conditions in real-world clinical settings—whether in emergency departments, primary care, or inpatient wards.

Why it matters today: - Croup and epiglottitis are life-threatening upper airway emergencies requiring rapid intervention. - RSV bronchiolitis is the leading cause of infant hospitalisation in winter. - Asthma is the most common chronic childhood disease, with acute exacerbations causing preventable morbidity. Mastering these conditions saves lives, reduces hospital stays, and improves long-term outcomes.


Why It Matters

Real-World Impact

Condition Key Problem Solved Consequences of Misdiagnosis/Mismanagement
Croup Prevents airway obstruction in toddlers with barking cough and stridor. Respiratory failure, intubation, ICU admission.
Epiglottitis Rapidly secures a swollen epiglottis before complete airway occlusion. Sudden death from asphyxiation.
RSV Bronchiolitis Manages hypoxia and feeding difficulties in infants with wheeze and secretions. Respiratory distress, dehydration, apnoea, prolonged hospitalisation.
Asthma Controls chronic inflammation and prevents acute exacerbations. Frequent ED visits, school absenteeism, lung function decline.

Industry relevance: - Emergency medicine: Fast, accurate diagnosis prevents intubation and ICU transfers. - Primary care: Early recognition reduces hospital admissions. - Public health: RSV and asthma management reduces healthcare costs and improves quality of life.


Core Concepts

1. Pathophysiology: Why These Conditions Differ

Condition Primary Pathophysiology Key Anatomical Site Age Group Most Affected
Croup Viral (parainfluenza) inflammation of the larynx and trachea-subglottic oedema. Subglottis (narrowest airway in kids) 6 months – 3 years
Epiglottitis Bacterial (Haemophilus influenzae type b) infection-supraglottic swelling. Epiglottis 2–7 years (rare post-Hib vaccine)
RSV Bronchiolitis Viral (RSV) infection-bronchiolar inflammation, mucus plugging, air trapping. Small airways (bronchioles) <2 years (peak: 2–6 months)
Asthma Chronic airway hyperresponsiveness + inflammation-reversible bronchoconstriction. Bronchi (large and small) All ages (common >2 years)

2. Clinical Red Flags (When to Worry)

Condition Red Flags Action Required
Croup Stridor at rest, retractions, cyanosis, drooling, lethargy. Nebulised adrenaline + steroids + O?
Epiglottitis Tripod position, muffled voice, no cough, drooling, toxic appearance. Do NOT examine throat-secure airway.
RSV Bronchiolitis Apnoea, SpO? <90%, poor feeding, severe retractions, grunting. O? + NG feeds + suction
Asthma Silent chest, inability to speak, SpO? <92%, exhaustion. High-flow O? + nebulised salbutamol + steroids

3. Key Investigations

Condition Diagnostic Test What It Shows
Croup Clinical diagnosis (Westley Croup Score). Barking cough, stridor, retractions.
Epiglottitis Lateral neck X-ray (thumb sign). Swollen epiglottis.
RSV Bronchiolitis Nasopharyngeal aspirate (NPA) for RSV PCR. Confirms RSV (not always needed).
Asthma Spirometry (if >5 years), peak flow (if >6 years). Reversible airflow obstruction.

4. Management Principles

Condition First-Line Treatment Second-Line/Severe
Croup Dexamethasone (0.6 mg/kg PO/IM) + supportive care. Nebulised adrenaline (1:1000, 5 mL).
Epiglottitis Secure airway (intubation by anaesthetist) + IV ceftriaxone. ICU admission.
RSV Bronchiolitis Oxygen (if SpO? <90%) + nasal suction + NG feeds if poor intake. High-flow nasal cannula (HFNC).
Asthma Salbutamol (2.5–5 mg nebulised) + prednisolone (1–2 mg/kg PO). IV magnesium sulphate, aminophylline.

How It Works: Clinical Approach

Step-by-Step Assessment

  1. ABCDE Approach (Always Start Here)
  2. Airway: Listen for stridor (croup/epiglottitis) or wheeze (asthma/RSV).
  3. Breathing: Count respiratory rate (tachypnoea = distress).
  4. Circulation: Check pulse (tachycardia = hypoxia/dehydration).
  5. Disability: Assess alertness (lethargy = severe hypoxia).
  6. Exposure: Look for retractions, cyanosis, rash.

  7. Differentiate Upper vs. Lower Airway

  8. Upper airway (croup/epiglottitis): Stridor, hoarse voice, barking cough.
  9. Lower airway (RSV/asthma): Wheeze, prolonged expiration, crackles.

  10. Severity Grading

  11. Croup: Westley Score (mild/moderate/severe).
  12. Asthma: PRAM Score (Paediatric Respiratory Assessment Measure).
  13. RSV: Bronchiolitis Severity Score (mild/moderate/severe).

  14. Decide: Home vs. Hospital

  15. Home: Mild croup (no stridor at rest), mild asthma (no hypoxia).
  16. Hospital: Severe croup (stridor at rest), epiglottitis, RSV with SpO? <90%, asthma with silent chest.

Hands-On: Managing an Acute Case

Prerequisites

  • Knowledge: Basic paediatric airway anatomy, ABCDE approach.
  • Equipment:
  • Pulse oximeter, nebuliser, oxygen, suction, IV access.
  • Medications: Dexamethasone, adrenaline, salbutamol, prednisolone.

Step-by-Step: Child with Croup (Moderate-Severe)

  1. Assess:
  2. 18-month-old with barking cough, stridor at rest, retractions.
  3. SpO? 92% on room air, RR 40, HR 150.

  4. Intervene: ```plaintext

  5. Give dexamethasone 0.6 mg/kg PO (or IM if vomiting).
  6. Administer nebulised adrenaline (1:1000, 5 mL) via face mask.
  7. Apply oxygen (1–2 L/min via nasal cannula) if SpO? <92%.
  8. Monitor closely for worsening stridor or lethargy. ```

  9. Expected Outcome:

  10. Stridor improves within 30 minutes of adrenaline.
  11. Child discharged home after 2–4 hours of observation if stable.

Step-by-Step: Infant with RSV Bronchiolitis

  1. Assess:
  2. 6-month-old with wheeze, crackles, poor feeding, SpO? 88%.

  3. Intervene: ```plaintext

  4. Apply oxygen (via nasal cannula) to maintain SpO? >90%.
  5. Perform nasal suctioning (bulb syringe or wall suction).
  6. Start NG feeds if unable to feed orally.
  7. Consider HFNC if severe (e.g., RR >70, apnoea). ```

  8. Expected Outcome:

  9. Oxygen weaned over 24–48 hours.
  10. Discharged when feeding well, SpO? >90% on room air.

Common Pitfalls & Mistakes

Mistake Why It Happens How to Avoid
Misdiagnosing croup as asthma Wheeze in croup can mimic asthma. Croup has stridor, not wheeze. Asthma has prolonged expiration.
Examining throat in epiglottitis Curiosity or lack of awareness. Do NOT use a tongue depressor-can trigger complete airway obstruction.
Overusing bronchodilators in RSV Wheeze in RSV is due to mucus plugging, not bronchospasm. Salbutamol is ineffective in RSV (use suction + O? instead).
Underestimating asthma severity Assuming "mild wheeze" in a child who is tachycardic and lethargic. Silent chest = severe asthma-treat aggressively.
Discharging too early Pressure to free up beds or parental request. Observe for 2–4 hours post-treatment (rebound symptoms are common).

Best Practices

1. Communication with Parents

  • Croup: "This is a viral infection causing a barking cough. Steroids will reduce swelling in the airway."
  • Epiglottitis: "This is an emergency. We need to secure the airway first, then give antibiotics."
  • RSV: "This virus causes mucus buildup. Suctioning and oxygen will help your baby breathe easier."
  • Asthma: "This is a long-term condition. We’ll adjust medications to prevent flare-ups."

2. Discharge Criteria

Condition Discharge When...
Croup No stridor at rest, SpO? >92% on room air, tolerating fluids.
Epiglottitis Extubated, afebrile, completing antibiotics.
RSV Bronchiolitis SpO? >90% on room air, feeding well, minimal respiratory distress.
Asthma No wheeze, PEF >75% predicted, no nocturnal symptoms.

3. Prevention Strategies

  • Croup/RSV: Hand hygiene, avoid sick contacts, palivizumab (for high-risk infants).
  • Epiglottitis: Hib vaccine (dramatically reduced cases).
  • Asthma: Inhaled corticosteroids (ICS), asthma action plan, trigger avoidance.

Tools & Frameworks

Clinical Scores

Tool Use Case How to Apply
Westley Croup Score Grades croup severity (mild/moderate/severe). Score 0–17 (higher = worse). >8 = severe.
PRAM Score Assesses asthma severity in children. Score 0–12 (higher = worse). >8 = severe.
Bronchiolitis Score Grades RSV severity (mild/moderate/severe). Score 0–12 (higher = worse). >6 = hospital admission.

Equipment

Tool When to Use
Nebuliser Croup (adrenaline), asthma (salbutamol).
High-Flow Nasal Cannula (HFNC) RSV bronchiolitis with severe hypoxia.
Pulse Oximeter All conditions (SpO? <90% = hypoxia).
Suction (Yankauer/bulb) RSV bronchiolitis (mucus clearance).

Real-World Use Cases

1. Emergency Department: Child with Stridor

  • Scenario: 2-year-old presents at 2 AM with barking cough, stridor, retractions.
  • Action:
  • Dexamethasone 0.6 mg/kg PO (or IM if vomiting).
  • Nebulised adrenaline if stridor at rest.
  • Observe for 2–4 hours-discharge if improved.
  • Outcome: Avoids intubation, reduces ED crowding.

2. Paediatric Ward: Infant with RSV

  • Scenario: 4-month-old with wheeze, poor feeding, SpO? 88%.
  • Action:
  • Oxygen via nasal cannula (target SpO? >90%).
  • Nasal suctioning before feeds.
  • NG feeds if unable to feed orally.
  • HFNC if severe (RR >70, apnoea).
  • Outcome: Prevents respiratory failure, shortens hospital stay.

3. Primary Care: Asthma Exacerbation

  • Scenario: 7-year-old with wheeze, cough, PEF 50% predicted.
  • Action:
  • Salbutamol 4–6 puffs via spacer (repeat every 20 mins).
  • Prednisolone 1–2 mg/kg PO (max 60 mg).
  • Refer to ED if no improvement in 1 hour.
  • Outcome: Prevents hospital admission, improves lung function.

Check Your Understanding (MCQs)

Question 1

A 2-year-old presents with a barking cough, stridor at rest, and retractions. What is the most appropriate first-line treatment?

A. Oral amoxicillin B. Nebulised salbutamol C. Oral dexamethasone D. IV ceftriaxone

Correct Answer: C. Oral dexamethasone Explanation: This child has moderate-severe croup, where dexamethasone (0.6 mg/kg) is first-line to reduce airway oedema. Why the Distractors Are Tempting: - A (Amoxicillin): Croup is viral (parainfluenza), so antibiotics are not indicated. - B (Salbutamol): Used for asthma, not croup (wheeze vs. stridor). - D (Ceftriaxone): Used for epiglottitis, not croup.


Question 2

A 6-month-old with wheeze, crackles, and SpO? 88% is diagnosed with RSV bronchiolitis. Which intervention is most likely to improve oxygenation?

A. Nebulised salbutamol B. Nasal suctioning C. Oral prednisolone D. IV fluids

Correct Answer: B. Nasal suctioning Explanation: RSV causes mucus plugging in small airways. Suctioning clears secretions and improves oxygenation. Why the Distractors Are Tempting: - A (Salbutamol): Ineffective in RSV (no bronchospasm). - C (Prednisolone): Steroids do not help in RSV bronchiolitis. - D (IV fluids): Helps dehydration but does not improve oxygenation.


Question 3

A 4-year-old with asthma presents with silent chest, SpO? 89%, and inability to speak. What is the next best step?

A. Oral prednisolone B. Nebulised salbutam