Which drug is commonly given to prevent acute transplant rejection? 2. What is seen on renal biopsy in acute transplant rejection? 3. MOA of cyclosporine?

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How do you remember renal physiology?
Use the mnemonic, A WET BED: A) maintenance of ACID-base balance; W) maintenance of WATER balance; E) balance of ELECTROLYTES; T) removal of TOXINS; B) control of BLOOD pressure; E) production of ERYTHROPOIETIN; and D) metabolism of vitamin D.

1. Which drug is commonly given to prevent acute transplant rejection? 2. What is seen on renal biopsy in acute transplant rejection? 3. MOA of cyclosporine?

1. Liddle syndrome 2. Epithelial Na channel 3. Autosomal dominant, hypertension + hypkoemic metabloic alkylosis. Gain of function mutation in an epithelial Na channel (ENaC) = inc. reabsorption of sodium. This causes hypertension and increased potassium excretion and decreased aldosterone production and increased hydrogen excretion. 4. Potassium sparring diuretics such as triamteren and amiloride but not spironolactone or eplerenone since not caused by aldosterone excess.
1. Cyclosporine 2. Dense interstitial mononuclear (lymphocytic) cell infiltration and vasculitis. 3. Inhibits IL-2 = decreased activation of CD4 and CD8
1. Acute interstitial nephritis: Oliguria fever, rash and eosinophils seen in urine. 2. NSAIDS, penicillin, cephalosporins, sulfas, Dirueticsm allopurinal, Cimetidin, PPIs. 3. Inflammation of renal interstitium. A hypersensitivity reaction to the drugs. 4. Renal papillary necrosis.
1. Auto anti bodies to type 4 collagen found in basement membrane in lungs (pulmonary alveoli), kidney(Renal glomeruli) and lens of eye. 2. Linear deposits of IgG 3. Rapidly progressive glomerulonephritis (cresenteric) and pulmonarry hemorrhage. 4. Plasma exchange.

Which drug is commonly given to prevent acute transplant rejection? 2. What is seen on renal biopsy in acute transplant rejection? 3. MOA of cyclosporine?

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Which drug is commonly given to prevent acute transplant rejection? 2. What is seen on renal biopsy in acute transplant rejection? 3. MOA of cyclosporine?

❤ If you liked Fatskills, consider supporting us by checking out The Life Manuals You Never Got.

About | Explore | User Guide | Topics | Subjects | Doubt Solver | Career Aptitude Test | Answers | Free Tools | What Should We Know? Privacy | Terms |

Without work one finishes nothing. - Ralph Waldo Emerson© 2026 Fatskills.com

All trademarks, logos and brand names are the property of their respective owners. All company, product and service names used in this website are for identification purposes only. Use of these names, trademarks and brands does not imply endorsement.

About | Explore | User Guide | Topics | Subjects | Doubt Solver | Career Aptitude Test | Answers | Free Tools | What Should We Know?
Privacy | Terms |

Without work one finishes nothing. - Ralph Waldo Emerson
© 2026 Fatskills.com