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A 35 yo man comes to GP. 1 week history of rash on lower legs. It is not painful or itchy. Also has diffuse joint pain. Has history of alchol abuse. Recently has been drinking 12-14 drinks pe day for past couple months. Vitals are normal. Exam shows petechiae, pinpoint hemorrhage, coiled hair on lower extremities. Oropharyngeal exam shows bleeding gums and dental caries. 1. What is diagnosis and why? 2. What defect in what reaction is responsible for patients symptoms?

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Connective tissue is the most abundant type of tissue in the body. It serves to connect and support other tissues and also has regulatory and immunologic functions. Connective tissue consists of cells, mainly fibroblasts, and an extracellular matrix (ECM).


1. A 35 yo man comes to GP. 1 week history of rash on lower legs. It is not painful or itchy. Also has diffuse joint pain. Has history of alchol abuse. Recently has been drinking 12-14 drinks pe day for past couple months. Vitals are normal. Exam shows petechiae, pinpoint hemorrhage, coiled hair on lower extremities. Oropharyngeal exam shows bleeding gums and dental caries. 1. What is diagnosis and why? 2. What defect in what reaction is responsible for patients symptoms?





 
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