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Pathophysiology Practice Test: Alterations of Hematologic Function in Children
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Similar to the anemias of adulthood, ineffective erythropoiesis or premature destruction of erythrocytes causes the anemias of childhood. The most common cause of insufficient erythropoiesis is iron deficiency. The other options may be causes but are not common ones.

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Pathophysiology Practice Test: Alterations of Hematologic Function in Children
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25 Questions

1. Which laboratory test will assist the nurse in identifying infants who are prone to develop hemolytic disease of the newborn (HDN)?
2. A 3-year-old child presents with bruising on the legs and trunk and a petechial rash. The mother also reports frequent nosebleeds. Lab tests reveal a decreased platelet count. This symptomology supports which medical diagnosis?
3. By what other name is the clotting factor IX disorder, hemophilia B known as?
4. Which major symptom indicates to the nurse that patient diagnosed with sickle cell anemia is experiencing a vasoocclusive crisis?
5. What is a priority assessment for Hodgkin lymphoma in children?
6. In the United States, which group of people should be assessed first for sickle cell disease?
7. Sickled cells will be removed from circulation mostly by the:
8. A 5-year-old male is diagnosed with immune thrombocytic purpura (ITP). What is the most common cause of this condition?
9. What is the most common form of childhood leukemia?
10. A 12-month-old toddler weighing 18 pounds is brought to the clinic because of weakness, slow physical growth, and developmental delays. His mother reports that the only food he will consume is cow’s milk. The symptoms support a diagnosis of which form of anemia?
11. A mother has a child that is diagnosed with sickle cell anemia. While the mother does not have the disease, which characteristic of her genetic makeup is responsible for the child’s disease?
12. Which mother-fetus combination is at most risk for a maternal-fetal blood incompatibility?
13. Testing reveals that a child has hemophilia A. This bleeding disorder results from a deficiency in factor:
14. The alpha and beta thalassemias are inherited in an _____ fashion.
15. Autopsy on a stillborn fetus reveals cardiomegaly, hepatomegaly, edema, and ascites as well as fulminant intrauterine congestive heart failure. Considering these findings, what is the most likely cause of death?
16. A 16-month-old female presents with tachycardia, pallor, anorexia, and systolic murmur. The nurse is checking the lab results, and the hemoglobin determination indicates a level below _____ grams per deciliter.
17. If an infant has hydrops fetalis, which type of thalassemia does the nurse suspect?
18. A 6-year-old male presents with fatigue, jaundice, and irritability. A blood smear shows the presence of sickled cells. Erythropoiesis is compromised in this child; which crisis should the nurse monitor the patient for?
19. Which of the following clusters of symptoms would lead the nurse to suspect a child has immune thrombocytopenic purpura (ITP)?
20. A 2-year-old male presented with growth and maturation retardation and splenomegaly. He died shortly after arriving at the ER. Autopsy revealed thalassemia secondary to defective:
21. Which of the following amino acids is present in Hb S and not present in normal Hb?
22. Which type of sickle cell crisis occurs only in young children?
23. What is the most likely cause of death associated with sickle cell disease?
24. What is the most serious complication of immune thrombocytopenic purpura (ITP)?
25. A 1-year-old female is diagnosed with anemia secondary to insufficient erythropoiesis. The most likely cause is:

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