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GRE Chromosomal And Molecular Basis Of Inheritance
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GRE Chromosomal And Molecular Basis Of Inheritance
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1. The new strand of DNA moving in the direction away from the replication fork. Synthesized as a series of segments in contrast to the leading strand that elongates continuously.

2. The general term for a chromosomal alteration in which an organism has more than two complete chromosome sets. There are more specific terms like triploidy (3n) and tetraploidy (4n) indicating 3 or 4 chromosomal sets - respectively.

3. An enzyme that catalyzes elongation of new DNA at a replication fork. As individual nucleotides align with complementary nucleotides along a template strand of DNA - DNA polymerase adds them to the growing end of the new DNA strand one by one.

4. A result of nondisjuction of sex chromosomes. Females are healthy and cannot be distinguished phenotypically from other females.

5. The most common type of translocation. A type of change in chromosome structure as a result of some sort of chromosomal breakage. In this - nonhomologous chromosome exchange fragments.

6. A cancer implicated by chromosomal translocations. The exchange of a larger portion of chromosome 22 with a small fragment from a tip of chromosome 9 produces a much shorted - easily recognized chromosome 22 - called the Philadelphia chromosome. Affe

7. Adenine doubles bonds thymine and guanine triple bonds cytosine.

8. The system for determining sex in most species of bees and ants. There are no sex chromosomes in these species - Females develop from fertilized ova and are thus diploid. Males - however - develop from unfertilized ova and are haploid; they have no f

9. In this - all four strands of DNA following replication have a mixture of old and new DNA. Proved incorrect and support came out for the semiconservative model.

10. Or phages. Viruses that infect bacteria.

11. Special site on a DNA molecule which replication begins. Indicated by a specific sequence of nucleotides.

12. Traits that are alternatives to the wild type because they are due to alleles assumed to have arisen as changes - or mutations - in the wild-type allele.

13. Traits that depend on which parent passed along the alleles for those traits. An exception to the display of Mendelian inheritance.

14. DNA repair that involves cleaving by nuclease and gap refilling by DNA polymerase and ligase.

15. Helps in repairing and proofreading DNA. An enzyme that cuts out a segment of the strand of DNA containing damage - creating a gap which is filled in with nucleotides properly paired with the nucleotides in the undamaged strand by DNA polymerase and

16. The segments of the lagging strand that get added to the template strand. The segments get joined together by DNA ligase.

17. A compact object that is the inactive X in each cell of a female. Although female mammals inherit two X chromosomes - one becomes almost completely inactivated during embryonic development and lies along the inside of the nuclear envelope. Most genes

18. The system for determining sex in birds - some fishes - and some insects. The sex chromosome present in the ovum determines the sex of offspring. The sex chromosomes are designated Z and W. Females are ZW and males are ZZ.

19. Genes located in organelles in the cytoplasm. Mitochondria and plastids contain small circular DNA molecules that carry genes coding for proteins and RNA and do not display Mendelian inheritance. For example - almost all the mitochondria come from th

20. Offspring that inherit a phenotype that matches one of the parental phenotypes.

21. A molecule that binds unpaired DNA strands - after its been separated by helicase - and stabilizes them until they serve as templates for the synthesis of new complementary strands.

22. A way of expressing distances between genes - defining one map unit as equivalent to a 1% recombination frequency.

23. Occurs when a mismatched nucleotide evades proofreading by DNA polymerase or arise after DNA synthesis is completed.

24. A result of nondisjuction of sex chromosomes.

25. The mammalian system for determining sex. The sex of the offspring depends on whether the sperm cell contains an X chromosome or a Y.