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USMLE Hematology Question Bank
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Hematology is the study of blood and the disorders related to it. Human blood consists of blood cells and plasma. 

USMLE Hematology Question Bank
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25 Questions

1. Hepcidin release is increased by what cyotkine? 2. What cells in liver release hepcidin? 3. What does hepcidin do?

2. What is used to treat von willibrand disease?

3. What is aplastic anemia? 2. What is clinical presentation of it? 3. Failure of what causes it? 4. What are some causative organisms whose infection is known to cause aplastic anemia?

4. In paroxysmal nocturnal hemoglobinuria what is seen on flow cytometry?

5. Hemophilia A 1. What is the deficiency? 2. What is its mode of inheritance? 3. What effect is there on PT and aPTT? 4. What is treatment?

6. What is the MOA of ATRA? All Trans Retinoic Acid?

7. What is granuloma inguinale?

8. What CD's are positive in CLL? 2. What are cells seen on smear that are distincitive?

9. What sort of infections are people without spleens have increased susceptibility to? 2. Which is most common? 3. What sort of organism is this?

10. What is the cause of the sickle shape in sickle cell anemia? 2. What causes the cells to sickle? 3. How are these sickles removed? What is this called?

11. Warm hemolytic anemia is caused by which antibodies?

12. Briefly what is pathophys of heparin induced thrombocytopenia?

13. In multiple myeloma what is the abnormal plasma cell seen in bone marrow biopsies called? 2. What is inside the bodies seen inside those abnormal plasma cells?

14. What inheritance is VWF disease? 2. What are features of VWF (in women)? 3. Briefly what is the pathophys of VWF disease? 4. What drug can be given that will improve menorrhagia and other symptoms? How does it work?

15. What is pyruvate kinase deficiency? 2. What can this cause?

16. What are the features of transfusion-associated circulatory overload (TACO)? 2. What is the treatment of choice broadly speaking? 3. What must a TACO be distinguished from? What is likely the cause of this condition?

17. What is the inheritance of G6PD deficiency? 2. What 2 molecule is decreased in G6PD deficiency? 3. What are common stresses that can induce hemolysis in G6PD deficiency?

18. Where is iron absorbed in the GIT? 2. Which procedure for obesity can bypass this region? 3. What is Total iron binding capacity a measure of?

19. A child who has a mutated defective enzyme responsible for catalyzing the last step in glycolysis has what condition? 2. What does this condition cause an accumulation of? 3. What does this accumulation cause?

20. What complication right after post partum can cause DIC? 2. What will you see on peripheral blood smear?

21. What is the most common type of drug induced thrombocytopenia? 2. What is the treatment for HIT?

22. What is immune thrombocytopenic purpura? 2. What are common symptoms?

23. What CDs are associated with AML?

24. How does childhood immune thrombocytopenic purpura present most commonly? 2. How is it usually diagnosed?

25. Autosplenecetomy is characteristic of what hematological disease? 2. Why does it occur?

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